Objectively measured physical activity relates to night-time blood pressure in older adults: cross-sectional analysis in the HEIJO-KYO cohort.
Objectively measured physical activity relates to night-time blood pressure in older adults: cross-sectional analysis in the HEIJO-KYO cohort.
复制标题
客观测量的体力活动与老年人夜间血压相关：HEIJO-KYO 队列的横断面分析。
DOI：
10.1097/hjh.0000000000002302
复制
发表时间：
2020
期刊：
影响因子：
--
通讯作者：
et al.
中科院分区：
文献类型：
--
作者：
Yamagami Y;Saeki K;Tai Y;Maegawa T;Iwamoto J;Kataoka H;et al.
目的：从预后来看，夜间血压(BP)比其他血压参数更重要。方法：这项横断面研究对1111名老年人(平均年龄71.8岁)进行了体力活动测量。结果：夜间平均收缩压和舒张压分别为115.9毫米汞柱和67毫米汞柱，日间平均体力活动量为299.2次/分(104.3次)。调整潜在混杂因素的多变量线性回归分析显示，白天平均体力活动较多与夜间收缩压降低显著相关(每百次/分钟增量的回归系数−为1.18；95%可信区间−为2.10至−0.26)和舒张压(−0.69；95%可信区间−1.17至−0.17)。活动阈值以上时间与夜间收缩压显著相关(≥500次/分钟：每对数分钟增量的回归系数，−1.61，95%CI−3.14至−0.08；≥1000次/分钟：−1.00，95%CI−1.97至−0.03；≥1500次/分钟：−1.13，95%CI−2.11至−0.14)。未服用降压药的亚组分析显示，活动阈值以上时间与夜间收缩压显著相关(≥5 0 0次/分钟：−2 94；95%CI−5.2 0对−0.68)。结论：客观测量的老年人白天体力活动与夜间血压呈显著负相关。进一步的纵向研究将确定体力活动对夜间血压的影响。
Objectives:Prognostically, night-time blood pressure (BP) is more important than other BP parameters. Previous physiological studies suggested physical exercise continuously decreases subsequent BP levels, although the association between daytime physical activity and night-time BP has not been evaluated in large populations.Methods:This cross-sectional study of 1111 older adults (mean age, 71.8 years) measured physical activity using actigraphy and ambulatory BP parameters.Results:The mean night-time SBP and DBP were 115.9 mmHg (SD, 16.2) and 67 mmHg (8.6), respectively, and the mean average daytime physical activity was 299.2 counts/min (104.3). A multivariable linear regression analysis, adjusted for potential confounders, suggested greater average daytime physical activity was significantly associated with lower night-time SBP (regression coefficient per 100 counts/min increment,− 1.18; 95% CI− 2.10 to− 0.26), and DBP (− 0.69; 95% CI− 1.17 to− 0.17). Significant associations between time above activity thresholds and night-time SBP were consistently observed (≥ 500 counts/min: regression coefficient per log min increment,− 1.61, 95% CI− 3.14 to− 0.08;≥ 1000 counts/min:− 1.00, 95% CI− 1.97 to− 0.03;≥ 1500 counts/min:− 1.13, 95% CI− 2.11 to− 0.14). A subgroup analysis without antihypertensive medications (n= 619) strongly associated time above activity thresholds with night-time SBP (≥ 500 counts/min:− 2.94; 95% CI− 5.20 to− 0.68). These results were consistent in the analysis using dipping as a dependent variable.Conclusion:Objectively measured daytime physical activity was significantly and inversely associated with night-time BP in older adults. Further longitudinal studies would ascertain effects of physical activity on night-time BP.