POPTREE2: Software for Constructing Population Trees from Allele Frequency Data and Computing Other Population Statistics with Windows Interface

POPTREE2: Software for Constructing Population Trees from Allele Frequency Data and Computing Other Population Statistics with Windows Interface
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DOI:
10.1093/molbev/msp312
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发表时间:
2010-04-01
影响因子:
10.7
通讯作者:
Tamura, Koichiro
Tamura, Koichiro
中科院分区:
生物学1区
文献类型:
--
作者:
Takezaki, Naoko;Nei, Masatoshi;Tamura, Koichiro

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目前,在许多研究领域中,需要具有易于访问的界面的软件来分析多态性数据,例如微卫星DNA和单核苷酸多态性。在这篇文章中,我们想宣布POPTREE 2,一个计算机程序包,可以执行等位基因频率数据的进化分析。原始版本(POPTREE)是一个在Windows和Unix的命令提示符下运行的命令行程序。在POPTREE 2遗传距离(种群间遗传分化程度的度量)构建系统发育树,平均杂合性(H)(种群内遗传变异的度量)和GST(细分种群遗传分化的度量)通过一个简单直观的Windows界面计算。这将有助于许多不同领域的研究人员进行多态性数据的统计分析。POPTREE 2可查阅http://www.med.kagawa-u.ac.jp/; genomelb/takezaki/poptree2/index.html。
Currently, there is a demand for software to analyze polymorphism data such as microsatellite DNA and single nucleotide polymorphism with easily accessible interface in many fields of research. In this article, we would like to make an announcement of POPTREE2, a computer program package, that can perform evolutionary analyses of allele frequency data. The original version (POPTREE) was a command-line program that runs on the Command Prompt of Windows and Unix. In POPTREE2 genetic distances (measures of the extent of genetic differentiation between populations) for constructing phylogenetic trees, average heterozygosities (H) (a measure of genetic variation within populations) and GST ( a measure of genetic differentiation of subdivided populations) are computed through a simple and intuitive Windows interface. It will facilitate statistical analyses of polymorphism data for researchers in many different fields. POPTREE2 is available at http://www.med.kagawa-u.ac.jp/;genomelb/takezaki/poptree2/index.html.