The physiology of gastric acid secretion.
The physiology of gastric acid secretion.
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胃酸分泌的生理学。
DOI：
10.1056/nejm198812293192605
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发表时间：
1988
期刊：
影响因子：
--
通讯作者：
Soll,AH
中科院分区：
文献类型：
--
作者：
Wolfe,MM;Soll,AH
哺乳动物胃是消化道的一个专门器官，用于储存和加工食物以供胃肠道吸收。胃的一个特征被认为是胃功能的标志，即分泌酸的能力;然而，胃酸的确切功能尚未完全了解。随着氢离子的分泌和胃内pH值降低到小于3.5，促进酶原胃蛋白酶原转化为活性蛋白水解胃蛋白酶。虽然一般认为蛋白质和其他食物的水解需要酸和胃蛋白酶，但患有氯霉素的人. ... . .
THE mammalian stomach is a specialized organ of the digestive tract that serves to store and process food for absorption by the intestine.1One of its features, considered to be the hallmark of gastric function, is the ability to secrete acid; however, the precise function of gastric acid is not completely understood. As hydrogen ions are secreted and intragastric pH decreases to less than 3.5, the conversion of the zymogen pepsinogen to active proteolytic pepsin enzymes is facilitated. Although it is generally assumed that acid and pepsin are required for the hydrolysis of proteins and other foods, persons with achlorhydria . . .