An Internet-based cancer clinical trials matching resource
An Internet-based cancer clinical trials matching resource
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DOI：
10.2196/jmir.7.3.e24
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发表时间：
2005-01-01
影响因子：
7.4
通讯作者：
Hampshire, M
中科院分区：
文献类型：
--
作者：
Metz, JM;Coyle, C;Hampshire, M
背景：现在许多患者通过互联网获取癌症临床试验信息。然而，提供临床试验招募信息的服务还没有很好地defined.Objectives：本研究描述了第一个基于Web的癌症临床试验匹配资源和成功匹配的用户的人口统计学特征。OncoLink是由宾夕法尼亚大学癌症中心（UPCC）管理的基于互联网的教育资源每月为超过385000个唯一的IP地址提供100万到200万页的服务。OncoLink推出了第一个在互联网上匹配资源的临床试验，允许患者通过安全连接输入人口统计数据，并与临床试验相匹配。与潜在的试验匹配的患者，预约方便与主要investigators.Results：虽然我们没有跟踪谁不能匹配的患者，627例谁提交了在线申请2002年1月至2003年4月之间成功匹配的潜在的临床试验招募。患者人群的平均年龄为56岁（范围18-88岁）。男性占患者人群的60%，超过90%的使用者为白人。大多数的应用程序是从结直肠癌（13%），肺癌（14%），黑色素瘤（10%），非霍奇金淋巴瘤（9%）的患者。结论：本报告显示，有相当数量的患者愿意使用互联网进行临床试验。必须注意接触来自各种社会经济和种族背景的患者。这个互联网资源有助于促进与癌症患者谁是预先筛选和激励参加临床试验的咨询。
Background: Many patients are now accessing the Internet to obtain cancer clinical trials information. However, services offering clinical trials recruitment information have not been well defined.Objectives: This study describes one of the first Web-based cancer clinical trials matching resources and the demographics of users who were successfully matched.Methods: OncoLink is the Internet-based educational resource managed by the University of Pennsylvania Cancer Center (UPCC) and serves between 1 and 2 million pages per month to over 385000 unique IP addresses. OncoLink launched one of the first clinical trials matching resources on the Internet that allowed patients to enter demographic data through a secure connection and be matched to clinical trials. For patients with matches to potential trials, appointments were facilitated with the principal investigators.Results: While we did not keep track of patients who could not be matched, 627 patients who submitted online applications between January 2002 and April 2003 were successfully matched for potential enrollment in clinical trials. The mean age of the patient population was 56 years (range 18-88 years). Males represented 60% of the patient population, and over 90% of users were Caucasian. Most of the applications were from patients with colorectal cancer (13%), lung cancer (14%), melanoma (10%), and non-Hodgkin's lymphoma (9%).Conclusions: This report shows that a significant number of patients are willing to use the Internet for enrolling in clinical trials. Care must be taken to reach patients from a variety of socioeconomic and racial backgrounds. This Internet resource helps to facilitate a consultation with a cancer patient who is prescreened and motivated to enroll in clinical trials.