Conservation of gene order: a fingerprint of proteins that physically interact
Conservation of gene order: a fingerprint of proteins that physically interact
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DOI:
10.1016/s0968-0004(98)01274-2
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发表时间:
1998-09-01
影响因子:
13.8
通讯作者:
Bork, P
中科院分区:
文献类型:
--
作者:
Dandekar, T;Snel, B;Bork, P
A systematic comparison of nine bacterial and archaeal genomes reveals a low level of gene-order (and operon architecture) conservation. Nevertheless, a number of gene pairs are conserved. The proteins encoded by conserved gene pairs appear to interact physically. This observation can therefore be used to predict functions of, and interactions between, prokaryotic gene products.