Colloidal dispersions of monodisperse magnetite nanoparticles modified with poly(ethylene glycol)
Colloidal dispersions of monodisperse magnetite nanoparticles modified with poly(ethylene glycol)
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DOI：
10.1016/j.jcis.2008.09.071
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发表时间：
2009-01-01
影响因子：
9.9
通讯作者：
Rinaldi, Carlos
中科院分区：
文献类型：
--
作者：
Barrera, Carola;Herrera, Adriana P.;Rinaldi, Carlos
以3-氨基丙基三乙氧基硅烷与羧酸-甲氧基PEG （mPEG-COOH）通过酰胺反应得到的硅烷功能化PEG为原料，合成了聚乙二醇修饰的单分散磁铁矿纳米颗粒。透射电子显微镜（TEM）、动态光散射（DLS）和zeta电位测量表明，颗粒呈单分散（sigma（gv）近似于0.2），在pH为3-9、离子强度为0.3 M NaCl的水中稳定存在。热重分析、TEM和DLS分析表明，颗粒表面形成了致密的接枝层。粒子间相互作用能的分析表明，聚乙二醇链之间的强空间排斥力稳定了粒子。(C) 2008爱思唯尔公司版权所有。
Monodisperse magnetite nanoparticles modified with poly(ethylene glycol) (PEG) were synthesized using a silane functionalized PEG obtained by reacting 3-aminopropyl triethoxysilane with carboxylic acid-methoxy PEG (mPEG-COOH) Using amide reactions. Transmission electron microscopy (TEM) dynamic, light scattering (DLS), and zeta potential measurements show the particles are monodisperse (sigma(gv) similar to 0.2) and stable in water for pH of 3-9 and ionic strengths, up to 0.3 M NaCl. Thermogravimetric analysis Coupled with TEM and DLS indicates formation of a dense graft layer oil the particle surface. An analysis of the interparticle interaction energy indicates that the particles are stabilized by strong steric repulsions between PEG chains on their surface. (C) 2008 Elsevier Inc. All rights reserved.