Identification of an antigen from normal human tissue that crossreacts with the carcinoembryonic antigen.

Identification of an antigen from normal human tissue that crossreacts with the carcinoembryonic antigen.
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从正常人体组织中鉴定与癌胚抗原发生交叉反应的抗原。

DOI:
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发表时间:
1972
影响因子:
11.1
通讯作者:
P. Burtin
P. Burtin
中科院分区:
综合性期刊1区
文献类型:
--
作者:
S. Kleist;G. Chavanel;P. Burtin

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被引文献

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存在于正常人体组织中的一种糖蛋白,其特征是既非器官特异性也非肿瘤特异性(非特异性交叉反应抗原),并与癌胚抗原交叉反应(通过Ouchterlony双扩散技术)。这种免疫学关系表明两种抗原分子上有共同的决定因素。我们证明非特异性交叉反应抗原不是癌胚抗原分子的片段。
A glycoprotein present in normal human tissue is characterized that is neither organ- nor tumor-specific (nonspecific crossreacting antigen) and that crossreacts (by the Ouchterlony double-diffusion technique) with the carcinoembryonic antigen. This immunological relationship indicates common determinants on the molecules of both antigens. We demonstrate that the nonspecific crossreacting antigen is not a fragment of the carcinoembryonic antigen molecule.