Parenthood following renal transplantation.
Parenthood following renal transplantation.
复制标题
肾移植后生育。
DOI：
10.1038/ki.1980.130
复制
发表时间：
1980
影响因子：
19.6
通讯作者：
Harris,P
中科院分区：
文献类型：
--
作者：
Penn,I;Makowski,EL;Harris,P
Sexual dysfunction is common in patients suffering from chronic renal failure. In one study of 519 patients, 48% of males and 26% of females encountered this problem [1]. Usually, females have loss of libido, anovulatory vaginal bleeding or amenorrhea, and males have loss of libido and impotence. During maintenance dialysis therapy, only 8% of medes and 6% of females experience improvement in sexual function. As a result, pregnancy occurs in only about 1 of 200 women of childbearing age having dialysis therapy [2]. Very few of these pregnancies result in live births at term [2–5]. Many patients experience improvement of sexual function following successful renal transplantation, however, and fertility increases. Thus, patients have the opportunity to become parents if they so desire [6, 7], and about 1 of every 50 women of childbearing age having a functioning renal transplant becomes pregnant [2].Average survival figures of large numbers of patients from all over the world indicate that between 61 and 78% of recipients of kidneys from related living donors are alive 5 years after transplantation, and with cadaver kidneys the figure is 42 to 51% [8]. Functional survival of the kidney graft at 5 years is 45 to 66% in recipients of living donor kidneys, and 29 to 35% in recipients of cadaver organs [8]. Currently, between 4,000 and 4,500 patients per year are undergoing renal transplantation in this country. As the number of long-term survivors is growing, it is important that physicians should be acquainted with the problems surrounding parenthood in these patients [6, 7]. This article will describe our experience in dealing with such individuals and their offspring.
