Double-Photon Emission Imaging With High-Resolution Si/CdTe Compton Cameras

Double-Photon Emission Imaging With High-Resolution Si/CdTe Compton Cameras
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DOI:
10.1109/tns.2021.3086799
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发表时间:
2021-08-01
影响因子:
1.8
通讯作者:
Shimazoe, Kenji
Shimazoe, Kenji
中科院分区:
工程技术3区
文献类型:
--
作者:
Orita, Tadashi;Yabu, Goro;Shimazoe, Kenji

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康普顿相机在核医学或小动物成像中的应用是一个具有挑战性的课题。一个主要问题是现有康普顿相机系统的空间分辨率不足。我们开发了一个由两台Si/CdTe康普顿相机组成的成像系统,这使我们能够研究各种放射性同位素的伽马-伽马符合成像,包括in -111,它每衰变发出171和245 keV的双光子,已经在核医学和许多商业化的放射性示踪剂中使用了很长时间。与传统方法相比,我们证明了该方法大大减少了点扩散函数的尾部,并在41.35 mm处获得了4.5 mm的半最大宽(FWHM)空间分辨率。
Application of Compton cameras to nuclear medicine or small animal imaging is a challenging subject. A major issue is insufficient spatial resolutions of the existing Compton camera systems. We developed an imaging system consisting of two Si/CdTe Compton cameras, which allows us to investigate gamma-gamma coincidence imaging for a variety of radioisotopes, including In-111, which emits double photons of 171 and 245 keV per decay and has been used for a long time in nuclear medicine and many commercialized radiotracers. We demonstrated with it a drastic reduction of a tail of the point spread function, compared with that of the traditional method, and obtained a spatial resolution of 4.5 mm full-width at half-maximum (FWHM) at 41.35 mm.