Binding of trivalent metal ions (Al3+, In3+, La3+) with phosphatidylcholine liposomal membranes investigated by microelectrophoresis
Binding of trivalent metal ions (Al3+, In3+, La3+) with phosphatidylcholine liposomal membranes investigated by microelectrophoresis
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DOI：
10.1140/epje/i2018-11679-6
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发表时间：
2018-05-29
影响因子：
1.8
通讯作者：
Figaszewski, Zbigniew A.
中科院分区：
文献类型：
--
作者：
Kotynska, Joanna;Figaszewski, Zbigniew A.
采用微电泳技术研究了三价金属离子（Al ~（3+）、In ~（3+）、La ~（3+））与磷脂酰胆碱（PC）脂质体的相互作用。测定了PC膜表面电荷密度和zeta电位对金属氯化物水溶液pH（pH范围为2 ~ 10）的依赖性。结果表明，Al ~（3+）、In ~（3+）和La ~（3+）离子在磷脂酰胆碱模型膜上的吸附，导致膜的电学性质发生变化。对磷脂酰胆碱脂质体膜与三价金属离子之间的平衡进行了理论探讨。提出了一个定量描述相互作用的数学模型。
Interactions between trivalent metal ions (Al3+, In3+, La3+) and phosphatidylcholine (PC) liposomes are studied by microelectrophoresis. The dependence of the PC membrane surface charge density and zeta potential on pH (pH range from 2 to 10) of the aqueous metal chloride solutions is determined. The obtained results indicate the adsorption of Al3+, In3+ and La3+ ions on phosphatidylcholine model membranes, leading to changes in the electrical properties of the membranes. The theoretical considerations on equilibria occurring between phosphatidylcholine liposomal membrane and trivalent metal ions are presented. A mathematical model describing the interactions in a quantitative way is proposed.