HIV-1 drug resistance genotype results in patients with plasma samples with HIV-1 RNA levels less than 75 copies/mL.
HIV-1 drug resistance genotype results in patients with plasma samples with HIV-1 RNA levels less than 75 copies/mL.
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HIV-1 耐药基因型导致患者血浆样本中 HIV-1 RNA 水平低于 75 拷贝/mL。
DOI：
10.1097/01.qai.0000232609.99705.a2
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发表时间：
2006
期刊：
影响因子：
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通讯作者：
Shafer,RobertW
中科院分区：
文献类型：
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作者：
Mitsuya,Yumi;Winters,MarkA;Fessel,WJeffrey;Rhee,Soo-Yon;Slome,Sally;Flamm,Jason;Horberg,Michael;Hurley,Leo;Klein,Daniel;Shafer,RobertW
从116例血浆HIV-1 RNA水平低于75拷贝/mL的患者的临床样本中获得HIV-1基因型耐药检测结果。在50例既往或随访基因型患者中，有49例证实了基因型有效性。认为基因型耐药检测在低水平病毒血症样本中不可靠的观点应该重新评估。
HIV-1 genotypic resistance test results were obtained on clinical samples from 116 patients with plasma HIV-1 RNA levels of less than 75 copies/mL. Genotype validity was confirmed in 49 of 50 patients with a previous or follow-up genotype. The belief that genotypic resistance testing is unreliable in samples with low-level viremia should be reassessed.