MR imaging of pulmonary parenchyma with a half-Fourier single-shot turbo spin-echo (HASTE) sequence

MR imaging of pulmonary parenchyma with a half-Fourier single-shot turbo spin-echo (HASTE) sequence
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DOI:
10.1016/s0720-048x(98)00167-3
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发表时间:
1999-02-01
影响因子:
3.3
通讯作者:
Edelman, RR
Edelman, RR
中科院分区:
医学3区
文献类型:
--
作者:
Hatabu, H;Gaa, J;Edelman, RR

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目的:评估半傅里叶单发涡轮自旋回波序列(HASTE)在描述肺实质和肺病理学方面的效用。方法和患者:将 HASTE 序列应用于 5 名正常志愿者和 20 名患有各种肺部疾病的患者,以描绘肺实质。通过 EGG 触发和屏气获取图像。在三名志愿者中,使用四个序列进行肺实质信号强度测量:(a)HASTE; (b) 常规自旋回波; (c) 帽子旋转回波:和 (d) 梯度回波。 T2 图是使用 HASTE 采集生成的。结果:观察到最小的呼吸或心脏运动伪影。对于 HASTE、自旋回波、快速自旋回波和梯度回波序列,肺实质的信噪比分别为 27.8 +/- 5.4、22.0 +/- 3.0、15.3 +/- 0.9 和 6.0 +/- 1.9。每个切片的 HASTE 扫描时间为 302 毫秒。右肺和左肺的收缩期 T2 值分别为 61.2 +/- 4.1 和 79.1 +/- 8.9 毫秒,舒张期为 92.6 +/- 5.8 和 97.5 +/- 12.2 毫秒(舒张期与收缩期的 P < 0.05)。 HASTE序列清楚地显示了各种肺部疾病,包括肺癌、肺门淋巴结肿大、小至3毫米的转移性肺结节、肺出血、肺水肿和支气管扩张中的支气管壁增厚。结论:我们的初步结果表明,HASTE 序列为肺实质屏气 MR 成像提供了一种实用方法。 (C) 1999 Elsevier Science Ireland Ltd. 保留所有权利。
Objective: To evaluate the utility of a half-Fourier single-shot turbo spin-echo sequence (HASTE) at depicting lung parenchyma and lung pathology. Methods and patients: A HASTE sequence was applied to five normal volunteers and 20 patients with various pulmonary disorders to depict the lung parenchyma. Images were acquired with EGG-triggering and breath-holding. In three volunteers, signal intensity measurements from lung parenchyma were performed using four sequences: (a) HASTE; (b) conventional spin echo; (c) hat spin echo: and (d) gradient echo. T2 maps were produced using the HASTE acquisition. Results: Minimal respiratory or cardiac motion artifacts were observed. The signal-to-noise ratios from lung parenchyma were 27.8 +/- 5.4, 22.0 +/- 3.0, 15.3 +/- 0.9, and 6.0 +/- 1.9 for HASTE, spin-echo, fast spin-echo, and gradient echo sequences, respectively. The scan time for HASTE was 302 ms for each slice. The T2 values in the right lung and the left lung were 61.2 +/- 4.1 and 79.1 +/- 8.9 ms in systole and 92.6 +/- 5.8 and 97.5 +/- 12.2 ms in diastole, respectively (P < 0.05 diastole versus systole). The HASTE sequence demonstrated clearly various pulmonary disorders, including lung cancer, hilar lymphadenopathy, metastatic pulmonary nodules as small as 3 mm, pulmonary hemorrhage, pulmonary edema and bronchial wall thickening in bronchiectasis. Conclusion: Our preliminary results indicate that the HASTE sequence provides a practical means for breath-hold MR imaging of lung parenchyma. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.