Face perception is mediated by a distributed cortical network
Face perception is mediated by a distributed cortical network
复制标题
DOI：
10.1016/j.brainresbull.2005.05.027
复制
发表时间：
2005-09-30
影响因子：
3.8
通讯作者：
Boesiger, P
中科院分区：
文献类型：
--
作者：
Ishai, A;Schmidt, CF;Boesiger, P
利用功能磁共振成像（fMRI）研究了人脑中与面孔知觉相关的神经系统。与许多专注于谨慎的面部反应区域的研究相反，本研究的目的是证明，无论刺激形式，情绪效价或任务要求如何，面部感知都会引起分布式皮层网络的激活。受试者观看了各种刺激（不熟悉的面孔和照片的线条画不熟悉的，著名的，和情绪化的面孔）和他们的相位扰乱版本。面部反应区域的网络被确定为包括枕下回、梭状回、上级颞沟、海马、杏仁核、额下回和眶额皮质。虽然在所有区域都发现了双侧激活，但右半球的反应更强。大脑半球的不对称性表现为更大、更显著的激活集群，以及更多的受试者表现出这种效应。感兴趣的区域分析显示，虽然所有的面部刺激都会在所有区域内引起激活，但观看着名和情绪化的面孔会导致更大的空间激活范围和更高的fMRI信号幅度。这些结果表明，仅仅是一张脸的记忆就足以在分布式皮层网络中定位激活，该网络介导了面部身份和表情的视觉分析。(c)2005年爱思唯尔公司All rights reserved.
The neural system associated with face perception in the human brain was investigated using functional magnetic resonance imaging (fMRI). In contrast to many studies that focused on discreet face-responsive regions, the objective of the current study was to demonstrate that regardless of stimulus format, emotional valence, or task demands, face perception evokes activation in a distributed cortical network. Subjects viewed various stimuli (line drawings of unfamiliar faces and photographs of unfamiliar, famous, and emotional faces) and their phase scrambled versions. A network of face-responsive regions was identified that included the inferior occipital gyrus, fusiform gyrus, superior temporal sulcus, hippocampus, amygdala, inferior frontal gyrus, and orbitofrontal cortex. Although bilateral activation was found in all regions, the response in the right hemisphere was stronger. This hemispheric asymmetry was manifested by larger and more significant clusters of activation and larger number of subjects who showed the effect. A region of interest analysis revealed that while all face stimuli evoked activation within all regions, viewing famous and emotional faces resulted in larger spatial extents of activation and higher amplitudes of the fMRI signal. These results indicate that a mere percept of a face is sufficient to localize activation within the distributed cortical network that mediates the visual analysis of facial identity and expression. (c) 2005 Elsevier Inc. All rights reserved.