Ultra-high resolution and long scan depth optical coherence tomography with full-phase detection for imaging the ocular surface.
Ultra-high resolution and long scan depth optical coherence tomography with full-phase detection for imaging the ocular surface.
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DOI：
10.2147/opth.s45122
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Wang J
中科院分区：
文献类型：
--
作者：
Tao A;Peterson KA;Jiang H;Shao Y;Zhong J;Carey FC;Rosen EP;Wang J
我们使用四种最先进技术的独特组合来实现适用于整个眼表成像的高性能光谱域光学相干断层扫描系统。超高分辨率、扩展深度范围、全相位干涉测量和高速互补金属氧化物半导体晶体管摄像头检测为大范围眼表的精确量化提供了前所未有的性能。我们证明了这种方法的可行性，通过获得高速和高分辨率的图像的模型眼超越角膜巩膜交界处。表面确定的图像与分割算法表现出良好的准确性和精度。
We used a unique combination of four state-of-the-art technologies to achieve a high performance spectral domain optical coherence tomography system suitable for imaging the entire ocular surface. An ultra-high resolution, extended depth range, full-phase interferometry, and high-speed complementary metal-oxide semiconductor transistor camera detection provided unprecedented performance for the precise quantification of a wide range of the ocular surface. We demonstrated the feasibility of this approach by obtaining high-speed and high-resolution images of a model eye beyond the corneal–scleral junction. Surfaces determined from the images with a segmentation algorithm demonstrated excellent accuracy and precision.