On the analysis of 1-nitronaphthalene, 1-nitropyrene and 6-nitrochrysene in cigarette smoke.
On the analysis of 1-nitronaphthalene, 1-nitropyrene and 6-nitrochrysene in cigarette smoke.
复制标题
卷烟烟气中1-硝基萘、1-硝基芘和6-硝基的分析
DOI：
10.1093/carcin/6.4.505
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发表时间：
1985
期刊：
影响因子：
4.7
通讯作者：
Hoffmann,D
中科院分区：
文献类型：
--
作者：
el-Bayoumy,K;O'Donnell,M;Hecht,SS;Hoffmann,D
以[14C]1-硝基萘、[14C]1-硝基芘和[14C]6-硝基芘为示踪剂和内标，建立了主流卷烟烟气中1-硝基萘、1-硝基芘和6-硝基芘的分析方法。收集香烟烟气冷凝水，通过一系列的溶剂划分和柱层析得到含有标记标准物的适当馏分。内标回收率为60 ~ 70%。采用毛细管气相色谱-电子捕获检测法和毛细管气相色谱-质谱联用法对各组分进行分析。1-硝基萘（<10ng/支）、1-硝基芘（<10ng/支）和6-硝基芘（<1ng/支）均未在肯塔基大学1R1香烟、美国85毫米非滤嘴香烟和法国70毫米非滤嘴香烟的主流烟雾中检测到。
A method was developed for the analysis of 1-nitro-naphthalene, 1-nitropyrene, and 6-nitrochrysene in main stream cigarette smoke, using [14C]1-nitronaphthalene, [14C]1-nitropyrene, and [14C]6-nitrochrysene as tracers and internal standards. Cigarette smoke condensate was collected and the appropriate fractions containing the labelled standards were obtained by a series of solvent partitions and column chromatography. Recovery of internal standards ranged from 60 to 70%. The fractions were analyzed by capillary gas chromatography with electron capture detection and by combined capillary gas chromatography – mass spectrometry. 1-Nitronaphthalene (<10ng/cigarette), 1-ni-tropyrene (<10ng/cigarette), and 6-nitrochrysene (<1ng/cigarette) were not detected in the mainstream smoke of the University of Kentucky 1R1 cigarette, a US commercial 85 mm non-filter cigarette, or a French commercial 70 mm non-filter cigarette.