Decreased cortical thickness & osteopenia in children with diabetes mellitus.
Decreased cortical thickness & osteopenia in children with diabetes mellitus.
复制标题
皮质厚度减少
DOI：
10.1210/jcem-45-4-845
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发表时间：
1977
期刊：
影响因子：
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通讯作者：
Virginia V. Weldon
中科院分区：
文献类型：
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作者：
Julio V. Santiago;William H. McAlister;S. Ratzan;Y. Bussman;Morey W. Haymond;G. Shackelford;Virginia V. Weldon
最近一项使用光子吸收技术的研究揭示了糖尿病成人中显著骨丢失的高频率，无论年龄或糖尿病持续时间如何。在这项研究中，107名4-18岁的糖尿病儿童进行了研究，使用皮质骨厚度和骨骼成熟作为骨发育的指标。总体而言，25%的糖尿病儿童的皮质厚度值低于正常儿童的5%限值。这在男孩中比女孩更常见，与糖尿病的持续时间无关。骨骼成熟延迟的适度增加并不能解释观察到的皮质变薄和骨质减少。糖尿病儿童骨量减少的原因至今仍是一个谜。
A recent study using the photon absorption technique has revealed a high frequency of significant bone loss in diabetic adults regardless of age or duration of diabetes. In this study 107 diabetic children age 4-18 were studied using cortical bone thickness and skeletal maturation as indicators of bone development. Overall, 25% of all diabetic children had cortical thickness values below the five percent limit for normal children. This was more common in boys than girls and was unrelated to duration of diabetes. A modest increase in delayed skeletal maturation did not account for the cortical thinning and osteopenia observed. The cause of the osteopenia of diabetic children remains an enigma.