A survey of nocturnal hypoxaemia and health related quality of life in patients with cryptogenic fibrosing alveolitis
A survey of nocturnal hypoxaemia and health related quality of life in patients with cryptogenic fibrosing alveolitis
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DOI：
10.1136/thorax.56.6.482
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发表时间：
2001-06-01
期刊：
影响因子：
10
通讯作者：
Hubbard, R
中科院分区：
文献类型：
--
作者：
Clark, M;Cooper, B;Hubbard, R
一项夜间血氧饱和度的调查进行了估计夜间低氧血症患者隐源性纤维化肺泡炎的患病率，并建立夜间低氧血症是否与quality of life. Methods相关隐源性纤维化肺泡炎出席诺丁汉市医院的所有患者被邀请进入研究。获得肺量测量和毛细血管血气张力，并在家中记录过夜血氧饱和度。生活质量进行了评估，使用简表-36，慢性呼吸问卷，医院焦虑抑郁量表，和Ep-worth嗜睡评分questionnaire.Results-Sixty 7符合条件的患者被确定和50同意进入研究，虽然后来被排除在外，因为他们已经使用氧气过夜。在其余48例患者中，平均（SD）过夜血氧饱和度（Sao）为92.5（4.3）%，每小时下降大于4%的中位数为2.3（四分位数范围1.5-5.3）。日间血氧水平预测夜间平均Sao，（1.94%/kPa，95%CI 1.22 - 2.66，p
Background-A survey of overnight oximetry was conducted to estimate the prevalence of nocturnal hypoxaemia in patients with cryptogenic fibrosing alveolitis and to establish whether nocturnal hypoxaemia is related to quality of life.Methods-All patients with cryptogenic fibrosing alveolitis attending Nottingham City Hospital were invited to enter the study. Spirometric measurements and capillary blood gas tensions were obtained and overnight oxygen saturation was recorded at home. Quality of life was assessed using the Short Form-36, Chronic Respiratory Questionnaire, Hospital Anxiety Depression Scale, and Ep-worth Sleepiness Score questionnaires.Results-Sixty seven eligible patients were identified and 50 agreed to enter the study, although two were subsequently excluded because they already used oxygen overnight. In the remaining 48 the mean (SD) overnight oxygen saturation (Sao,) was 92.5 (4.3)% and the median number of dips greater than 4% per hour was 2.3 (interquartile range 1.5-5.3). Daytime oxygen level predicted mean overnight Sao, (1.94%/kPa, 95% CI 1.22 to 2.66, p