Sensory evoked potentials in clinical disorders of the nervous system.
Sensory evoked potentials in clinical disorders of the nervous system.
复制标题
神经系统临床疾病中的感觉诱发电位。
DOI：
10.1146/annurev.ne.01.030178.000535
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发表时间：
1978
影响因子：
13.9
通讯作者：
A. Starr
中科院分区：
文献类型：
--
作者：
A. Starr
Ann. Rev，Neurosci. 1978. 13103-27版权（C3 1978年由年度评论;公司。感觉诱发电位011505神经系统临床疾病A. Starr Department of Neurology，University of加州Irvine Medical Center，橙子，加州92668引言目前临床医生在神经科学领域使用的诊断工具提供了关于神经系统结构的有用信息，但在提供对功能的了解方面不足。对于这一点，临床医生仍然必须依靠历史，体格检查，和病人自己的描述，他的经验障碍。对相对无创、简单的大脑功能测试的探索刺激了最近从头皮记录的感觉诱发电位的发展，作为低风险、临床适用的程序，能够提供有关各种神经系统功能的新的客观信息。在这篇评论中，我总结了各种应用听觉，视觉和体感诱发电位的临床神经系统疾病的研究在男人，开始与一个简短的描述所采用的刺激，正常模式的诱发电位，刺激和受试者变量，在acquisition这些电位，和他们可能的神经发生器。临床应用分析参考每个感觉系统，而不是根据疾病状态。表1列出了各种类型的听觉、视觉和体感诱发电位，这些诱发电位基于它们从沿着感觉通路的假定起源部位。诱发电位波形包括在图中，其记录的技术细节见表2。感觉诱发电位是最早用于研究大脑功能的方法之一（Lindsley 1969，Davis 1976，Bergamini & Bergamasco 1967）。虽然用于量化细胞内和单个神经元活动的技术现在在其他动物的研究中占主导地位，但对诱发电位的兴趣仍然存在，特别是用于分析人脑功能。此外，开发103 0147- 006 X/78/0325-0l03$01.00
Ann. Rev, Neurosci. 1978. 13103-27 Copyright (C3 1978 by Annual Review; Inc. All rightr reserved SENSORY EVOKED 011505 POTENTIALS IN CLINICAL DISORDERS OF THE NERVOUS SYSTEM A. Starr Department of Neurology, University of California Irvine Medical Center, Orange, California 92668 INTRODUCTION The diagnostic tools presently used by clinicians in the field of neuroscience provide useful information about the structure of the nervous system, but fall short with respect to providing insights into function. For this, the clinician must still rely on history, physical examination, and the patient’s own description of the experience of his disorder. The search for relatively noninvasive, simple tests of brain function has stimulated the recent development of sensory evoked potentials recorded from the scalp as low-risk, clinically applicable procedures capable of providing new and objective information about a variety of nervous system functions. In this review I summarize the various applications of auditory, visual, and somatosensory evoked potentials to the study of clinical neurological disorders in man, beginning with a brief description of the stimuli employed, normal patterns of evoked potentials, stimulus and subject variables that influence these potentials, and their probable neural generators. Clinical applications are analyzed with reference to each sensory system rather than according to disease states. Table 1 contains a listing of the various types of auditory, visual, and somatosensory evoked potentials based on their presumed sites of origin from along the sensory pathway. The evoked potential wave forms are included in the figures and the technical details of their recording are in Table 2. Sensory evoked potentials were among the earliest measures used to study the functions of the brain (Lindsley 1969, Davis 1976, Bergamini & Bergamasco 1967). While techniques for quantifying intracellular and single neuronal activity now predominate in the study of other animals, interest in evoked potentials persists particularly for the analysis of human brain functions. Moreover, the development 103 0147-006X/78/0325-0l03$01.00