Relative contribution of fat, protein, carbohydrate, and ethanol to intestinal hyperemia.
Relative contribution of fat, protein, carbohydrate, and ethanol to intestinal hyperemia.
复制标题
脂肪、蛋白质、碳水化合物和乙醇对肠道充血的相对贡献。
DOI：
10.1152/ajpgi.1982.242.1.g27
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发表时间：
1982
期刊：
影响因子：
--
通讯作者：
Chou,CC
中科院分区：
文献类型：
--
作者：
Siregar,H;Chou,CC
通过比较麻醉犬空肠中由标准高脂肪、高蛋白和高碳水化合物试验饲粮、玉米油和乙醇配制的各种溶液对血管和代谢的影响，评估膳食脂肪、蛋白质、碳水化合物和乙醇对餐后肠道充血的相对贡献。高脂肪饮食（45%脂肪，18%蛋白质，29%碳水化合物）产生的充血最多（对照组的+30.4%），其次是高蛋白（22%脂肪，64%蛋白质，4%碳水化合物）（+24.1%）和高碳水化合物（8%脂肪，18%蛋白质，68%碳水化合物）（+18.2%）饮食。当高碳水化合物饮食的脂肪含量提高到与高蛋白饮食的脂肪含量相等时，两种饮食产生的充血程度相同。与含有相同脂肪量的饮食相比，这三种饮食产生的充血明显更大。所有这些饮食解决方案都增加了肠道耗氧量。然而，乙醇在不改变氧气消耗的情况下增加了血流量。因此，在体重基础上，脂肪产生的充血最大，但蛋白质和碳水化合物对餐后肠道充血的贡献不能认为是微不足道的。充血是这三种饮食成分协同作用的结果。
The relative contribution of dietary fat, protein, carbohydrate, and ethanol to postprandial intestinal hyperemia was assessed by comparing the vascular and metabolic effects of luminal placement of various solutions prepared from standard high -fat, high-protein, and high-carbohydrate test diets, corn oil, and ethanol in the jejunum of anesthetized dogs. The high-fat diet (45% fat, 18% protein, 29% carbohydrate) produced the greatest hyperemia (+30.4% of control), followed by high-protein (22% fat, 64% protein, 4% carbohydrate) (+24.1%) and high-carbohydrate (8% fat, 18% protein, 68% carbohydrate) (+18.2%) diets. When the fat content of the high-carbohydrate diet was raised to equal that of the high-protein diet, the two diets produced the same degree of hyperemia. All three diets produced a significantly greater hyperemia than the solutions containing the same amount of fat. All these dietary solutions increased intestinal oxygen consumption. Ethanol, however, increased blood flow without altering oxygen consumption. Thus, on weight basis, fat produces the greatest hyperemia, but the contribution of protein and carbohydrate to postprandial intestinal hyperemia cannot be considered as insignificant. The hyperemia results from a synergistic effect of all three dietary components.