Incidence and demographics of childhood ptosis.
Incidence and demographics of childhood ptosis.
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DOI：
10.1016/j.ophtha.2010.10.026
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发表时间：
2011-06
期刊：
影响因子：
13.7
通讯作者：
Mohney BG
中科院分区：
文献类型：
--
作者：
Griepentrog GJ;Diehl NN;Mohney BG
报告在明确定义的人群中40年内诊断的儿童上睑下垂的发病率和人口统计学资料。回顾性、基于人群的队列研究。从1965年1月1日至2004年12月31日，明尼苏达州奥姆斯特德县居民中诊断为儿童上睑下垂的患者（< 19岁）。对罗切斯特流行病学项目确定的所有潜在患者的病历进行了审查。计算的年年龄和性别特异性发病率和人口统计学信息。在40年期间，共有107名儿童被诊断为上睑下垂，19岁以下儿童的发病率为7.9/100，000（95%置信区间[CI]：6.4-9.5）。107例中有96例（89.7%）为先天性发病，其中81例（75%）为单纯先天性上睑下垂，出生患病率为1/842。单纯性先天性上睑下垂患者中有12%有儿童期上睑下垂家族史。单纯性先天性上睑下垂双侧3例（4%），单侧55例（68%）累及左上睑（95%CI：57%~ 78%，p<0.001）。在19岁以下的儿童中，每10万例患者中有7.9例被诊断出上睑下垂（95% CI：6.4-9.5）。单纯性先天性上睑下垂是最常见的形式，发生在1/842出生，并显着更可能涉及左侧。
To report the incidence and demographics of childhood ptosis diagnosed over a 40-year period in a well-defined population. Retrospective, population-based cohort study. Patients (< 19 years) diagnosed with childhood ptosis as residents of Olmsted County, Minnesota, from January 1, 1965, through December 31, 2004 The medical records of all potential patients identified by the Rochester Epidemiology Project were reviewed. Calculated annual age- and sex-specific incidence rates and demographic information. A total of 107 children were diagnosed with ptosis during the 40-year period, yielding an incidence of 7.9/100,000 < 19 years (95% confidence interval [CI]: 6.4-9.5) of age. Ninety-six (89.7%) of the 107 were congenital in onset, 81 (75%) of which had simple congenital ptosis, yielding a birth prevalence of 1 in 842 births. A family history of childhood ptosis was present in twelve percent of queried patients with simple congenital ptosis. Three (4%) of the simple congenital ptosis cases were bilateral and 55 (68%) of the unilateral cases involved the left upper eyelid (95% CI: 57%-78%, p<0.001). Childhood ptosis was diagnosed in 7.9 per 100,000 patients less than 19 years (95% CI: 6.4-9.5). Simple congenital ptosis was the most prevalent form, occurring in 1 in 842 births, and significantly more likely to involve the left side.
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DOI：
10.1016/s0896-1549(05)70238-8
发表时间：
2001-09-01
期刊：
Ophthalmology clinics of North America
影响因子：
--
作者：
Alexandrakis, G;Saunders, R A
通讯作者：
Saunders, R A
影响因子：
--
作者：
CLARK, BJ;KEMP, EG;LEE, WR
通讯作者：
LEE, WR
影响因子：
13.7
作者：
Harrad, RA;Shuttleworth, GN
通讯作者：
Shuttleworth, GN
影响因子：
4.2
作者：
ISENBERG, S;URIST, MJ
通讯作者：
URIST, MJ
影响因子：
4.2
作者：
Steel, DHW;Harrad, RA
通讯作者：
Harrad, RA