The eukaryotic linear motif resource ELM: 10 years and counting.

The eukaryotic linear motif resource ELM: 10 years and counting.
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DOI:
10.1093/nar/gkt1047
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发表时间:
2014-01
影响因子:
14.9
通讯作者:
Gibson TJ
Gibson TJ
中科院分区:
生物学2区
文献类型:
--
作者:
Dinkel H;Van Roey K;Michael S;Davey NE;Weatheritt RJ;Born D;Speck T;Krüger D;Grebnev G;Kuban M;Strumillo M;Uyar B;Budd A;Altenberg B;Seiler M;Chemes LB;Glavina J;Sánchez IE;Diella F;Gibson TJ

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真核线性基序(ELM http://elm.eu.org))资源是收集、分类和整理有关短线性基序(SLIM)的信息的枢纽。10年来,这个资源为科学界提供了一本关于线性图案的生物学和功能的免费指南。当前版本的ELM包含∼200个不同的主题类和2400多个经过实验验证的实例,这些实例来自>2000科学出版物。此外,关于Motif介导的相互作用的详细信息已作了注释,并以标准交换格式提供。在适当的情况下,还提供了指向Switches.elm.eu.org和KEGG路径等资源的链接。
The eukaryotic linear motif (ELM http://elm.eu.org) resource is a hub for collecting, classifying and curating information about short linear motifs (SLiMs). For >10 years, this resource has provided the scientific community with a freely accessible guide to the biology and function of linear motifs. The current version of ELM contains ∼200 different motif classes with over 2400 experimentally validated instances manually curated from >2000 scientific publications. Furthermore, detailed information about motif-mediated interactions has been annotated and made available in standard exchange formats. Where appropriate, links are provided to resources such as switches.elm.eu.org and KEGG pathways.
DOI: 10.1016/s1093-3263(00)00138-8
发表时间: 2001-01-01
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