Pre-mRNA Splicing in Plants: In Vivo Functions of RNA-Binding Proteins Implicated in the Splicing Process.
Pre-mRNA Splicing in Plants: In Vivo Functions of RNA-Binding Proteins Implicated in the Splicing Process.
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DOI：
10.3390/biom5031717
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发表时间：
2015-07-24
期刊：
影响因子：
5.5
通讯作者：
Staiger D
中科院分区：
文献类型：
--
作者：
Meyer K;Koester T;Staiger D
高等植物中选择性的前信使RNA剪接在暴露于外源和内源信号后作为重要的调节层出现。因此，预测在剪接过程中发挥作用的RNA结合蛋白缺陷的突变株表现出严重的表型变化。其中包括发育缺陷，对病原体威胁或非生物应激因素的反应受损，以及昼夜节律系统的失调。在模式植物拟南芥中已经确定了一系列剪接因子。在这里，我们总结了关于这些剪接因素中的缺陷如何影响植物性能的最新见解。
Alternative pre-messenger RNA splicing in higher plants emerges as an important layer of regulation upon exposure to exogenous and endogenous cues. Accordingly, mutants defective in RNA-binding proteins predicted to function in the splicing process show severe phenotypic alterations. Among those are developmental defects, impaired responses to pathogen threat or abiotic stress factors, and misregulation of the circadian timing system. A suite of splicing factors has been identified in the model plant Arabidopsis thaliana. Here we summarize recent insights on how defects in these splicing factors impair plant performance.