Race, ethnicity and social class and the complex etiologies of asthma

Race, ethnicity and social class and the complex etiologies of asthma
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DOI:
10.2217/14622416.9.4.453
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发表时间:
2008-04-01
期刊:
影响因子:
2.1
通讯作者:
Burchard, Esteban Gonzalez
Burchard, Esteban Gonzalez
中科院分区:
医学4区
文献类型:
--
作者:
Drake, Katherine A.;Galanter, Joshua M.;Burchard, Esteban Gonzalez

文献摘要

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哮喘是一种常见但复杂的呼吸系统疾病,由遗传和环境因素相互作用引起。在患病率、死亡率和药物反应方面存在着明显的种族和族裔差异。这些差异可能是由于种族和族裔在遗传、环境、社会和心理风险因素方面的差异造成的。此外,种族、族裔和社会阶层是影响健康结果的不可计量因素的重要代表。在此,我们回顾了不同种族、民族和社会阶层的哮喘病因学的显著差异,并主张继续将其作为哮喘研究的变量。
Asthma is a common but complex respiratory disease caused by the interaction of genetic and environmental factors. Significant racial and ethnic disparities in prevalence, mortality and drug response have been described. These disparities may be explained by racial and ethnic-specific variation in genetic, environmental, social and psychological risk factors. In addition, race, ethnicity and social class are important proxies for unmeasured factors that influence health outcomes. Herein, we review salient differences in the etiologies of asthma by race, ethnicity and social class, and argue for their continued use as variables in asthma research.