Lung Segment Geometry Study: Simulation of Largest Possible Tumours That Fit into Bronchopulmonary Segments
Lung Segment Geometry Study: Simulation of Largest Possible Tumours That Fit into Bronchopulmonary Segments
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肺段几何研究：模拟适合支气管肺段的最大可能肿瘤
DOI：
10.1055/s-0030-1271009
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发表时间：
2012
影响因子：
1.5
通讯作者：
Stamatis
中科院分区：
文献类型：
--
作者：
Welter S;Stöcker C;Dicken V;Kühl H;Krass S;Stamatis
I期非小细胞肺癌（NSCLC）的节段性切除已经得到了很好的报道，并且被认为与肺叶切除术具有相似的生存率，但由于实质边缘不充分，局部肿瘤复发率增加。因此，今天只有当肿瘤小于2厘米时才进行节段切除术。方法对支气管肺段的11个薄层CT图像进行三维重建，并将虚拟球形肿瘤放置在肺段上，尊重肺段的所有边界。下一步，减去2 cm和3 cm的虚拟实质安全边界，计算剩余肿瘤的大小。结果右侧7 + 8节段最大肿瘤直径为26.1 mm，左侧根尖1 ~ 3节段最大肿瘤直径为59.8 mm，实质安全边界为30mm。结论：通过三维肺部CT扫描重建，我们证明了在适当的边缘下，即使对于某些病例中较大的肿瘤，节段切除术或节段组切除术也是可行的。
BackgroundSegmental resection in stage I non-small cell lung cancer (NSCLC) has been well described and is considered to have similar survival rates as lobectomy but with increased rates of local tumour recurrence due to inadequate parenchymal margins. In consequence, today segmentectomy is only performed when the tumour is smaller than 2 cm.MethodsThree-dimensional reconstructions from 11 thin-slice CT scans of bronchopulmonary segments were generated, and virtual spherical tumours were placed over the segments, respecting all segmental borders. As a next step, virtual parenchymal safety margins of 2 cm and 3 cm were subtracted and the size of the remaining tumour calculated.ResultsThe maximum tumour diameters with a 30-mm parenchymal safety margin ranged from 26.1 mm in right-sided segments 7 + 8 to 59.8 mm in the left apical segments 1–3.ConclusionsUsing a three-dimensional reconstruction of lung CT scans, we demonstrated that segmentectomy or resection of segmental groups should be feasible with adequate margins, even for larger tumours in selected cases.
影响因子：
4.6
作者：
Schuchert, Matthew J.;Pettiford, Brian L.;Landreneau, Rodney J.
通讯作者：
Landreneau, Rodney J.