Symptom assessment in schizophrenic prodromal states
Symptom assessment in schizophrenic prodromal states
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DOI：
10.1023/a:1022034115078
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发表时间：
1999-12-01
影响因子：
3.5
通讯作者：
Davidson, L
中科院分区：
文献类型：
--
作者：
Miller, TJ;McGlashan, TH;Davidson, L
患有精神分裂症的人经常遭受长期的缺陷。现有的治疗往往只是治标不治本，不能改善长期病程。与精神分裂症发病相关的神经生物学缺陷可能在这种终身疾病的早期阶段最为活跃和具有破坏性，这一事实已经将研究和临床工作的重点转移到这种疾病的早期或前驱阶段。有限的研究结果表明，早期干预可能会导致更好的预后。可以延迟或预防精神病发作的早期干预措施具有明显的公共卫生影响，并依赖于能够识别真正的前驱患者。前驱症状结构化访谈和前驱症状量表是为操作性定义诊断和定量评定精神病前驱患者症状严重程度而开发的评估工具。
Individuals who develop schizophrenia often suffer long standing deficits. All too often available treatments remain palliative and do not improve the long-term course of illness. The neurobiological deficits associated with the onset of schizophrenia may be most active and damaging in the early stages of this life long illness, a fact which has shifted the focus of research and clinical work: toward the early or prodromal stages of this disorder. Results from limited studies suggest that early intervention may lead to a better prognosis. Early interventions that could delay or prevent the onset of psychotic illnesses have obvious public health implications and rely on being able to identify true prodromal patients. The Structured Interview for Prodromal Symptoms and the Scale of Prodromal Symptoms are assessment instruments developed for operationally defining diagnosis and for quantitatively rating symptom severity for patients prodromal for psychosis.