GENERAL CARDIOVASCULAR RISK PROFILE - FRAMINGHAM STUDY
GENERAL CARDIOVASCULAR RISK PROFILE - FRAMINGHAM STUDY
复制标题
DOI：
10.1016/0002-9149(76)90061-8
复制
发表时间：
1976-01-01
影响因子：
2.8
通讯作者：
GORDON, T
中科院分区：
文献类型：
--
作者：
KANNEL, WB;MCGEE, D;GORDON, T
心血管疾病高危人群可通过测量其血清胆固醇和血压、吸烟史、心电图和葡萄糖耐受不良的测定来有效识别。用于识别处于心血管疾病的高风险的人的一个一般功能也有效地识别处于每种特定疾病的风险的人，所述特定疾病为冠心病、动脉粥样硬化血栓性脑梗塞、高血压心脏病和间歇性跛行，尽管所使用的变量对每种特定疾病有不同的影响。使用此功能确定为最高风险的10%的人占冠心病8年发病率的约五分之一和动脉粥样硬化血栓性脑梗塞、高血压性心脏病和间歇性跛行8年发病率的约三分之一。因此，该功能提供了一种经济有效的方法，用于识别需要预防性治疗的高心血管风险人群和无需对一个中度升高的风险特征感到震惊的低风险人群。
Persons at high risk of cardiovascular disease can be effectively identified from a measurement of their serum cholesterol and blood pressure, a smoking history, an electrocardiogram and a determination of glucose intolerance. One general function for identifying persons at high risk of cardiovascular disease is also effective in identifying persons at risk for each of the specific diseases, coronary heart disease, atherothrombotic brain infarction, hypertensive heart disease and intermittent claudication, even though the variables used have a different impact on each particular disease.The 10 percent of persons identified with use of this function as at highest risk accounted for about one fifth of the 8 year incidence of coronary heart disease and about one third of the 8 year incidence of atherothrombotic brain infarction, hypertensive heart disease and intermittent claudication. Hence the function provides an economic and efficient method of identifying persons at high cardiovascular risk who need preventive treatment and persons at low risk who need not be alarmed about one moderately elevated risk characteristic.