EP07.16: Visibility of fetal brain structures in blind ultrasound sweeps

EP07.16: Visibility of fetal brain structures in blind ultrasound sweeps
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EP07.16:盲超声扫描中胎儿大脑结构的可见性

DOI:
10.1002/uog.26725
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发表时间:
2023
影响因子:
7.1
通讯作者:
Aljishi F
Aljishi F
中科院分区:
医学1区
文献类型:
--
作者:
Aljishi F

文献摘要

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方法在一项前瞻性观察研究中,进行了盲超声扫描。由一名读者对 109 名受试者(81 名处于妊娠中期,28 名处于妊娠晚期)进行了手动评估。在所有扫描中手动标记了六个解剖结构:大脑镰中线、透明隔腔、侧脑室、脉络丛、小脑和小脑延髓池。在所有扫描中计算每个结构的可见性计数和百分比。结果所有评估的大脑结构在盲扫描中至少有 45% 的时间可见。这一比例在妊娠中期更高(> 55%)。最常见的结构是中线大脑镰(91/109(83%)受试者;(75/81(93%)在妊娠中期),其次是脉络丛(76/109(70%)受试者(72/81(89%)在妊娠中期)。透明隔腔、侧脑室、小脑和小脑延髓池在 46-53% 的病例(孕中期 57-61%)。 27 名 (25%) 受试者的所有结构的完整集都被可视化;妊娠中期有 25 例(31%),妊娠晚期仅有 2 例(7%)。结论 在相当大比例的病例中,胎儿大脑解剖结构在盲扫中可见,但这取决于个体结构,并且妊娠中期的可视化程度高于妊娠晚期。未来 工作应评估与其他读者和临床方法的一致性,以优化结构可视性,以便通过盲扫评估胎儿大脑解剖结构。
MethodsIn a prospective observational study, blind ultrasound sweeps were undertaken. Manual assessment was performed by one reader for 109 subjects (81 in second trimester, 28 in third trimester). Six anatomical structures were manually labelled across all sweeps: midline falx, cavum septi pellucidi, lateral ventricles, choroid plexus, cerebellum, and cisterna magna. The count and percentage of visibility of each structure were computed across all sweeps.ResultsAll assessed brain structures were visible in the blind sweeps at least 45% of the time. This was higher in the second trimester (> 55%). The most seen structure was the midline falx (91/109 (83%) subjects;(75/81 (93%) in the second trimester), followed by choroid plexus in (76/109 (70%) subjects (72/81 (89%) in the second trimester). Cavum septi pellucidi, lateral ventricles, cerebellum and cisterna magna were visible in 46-53% of cases (57-61% in the second trimester). The complete set of all structures were visualised in 27 (25%) subjects; 25 (31%) in the second and only 2 (7%) in the third trimester.ConclusionsFetal anatomical brain structures are visible in blind sweeps in a significant proportion of cases, but this depends on the individual structure and visualisation is higher in the second than the third trimester. Future work should assess agreement with additional readers and clinical methods for optimising structure visibility to allow assessment of fetal brain anatomy from blind sweeps.