Recording of dorsal raphe unit activity in vitro
Recording of dorsal raphe unit activity in vitro
复制标题
体外中缝背单位活动的记录
DOI：
10.1016/0304-3940(76)90014-8
复制
发表时间：
1976
影响因子：
2.5
通讯作者：
B. Jacobs
中科院分区：
文献类型：
--
作者：
S. Mosko;B. Jacobs
在400μm厚脑片上记录大鼠中脑中缝背核单个神经元的自发电活动。在活体记录中，大多数中缝神经元表现出缓慢而规则的放电模式，这是中缝神经元活动的特征。因此，这些神经元的体外活性为分析调节这些含5-羟色胺神经元活性的内源性和外源性因素提供了准备。
The spontaneous electrical activity of single neurons of the midbrain dorsal raphe nucleus in the rat was recorded in vitro in 400 μm thick slices. The majority of raphe neurons exhibited the slow and regular discharge pattern that characterizes the activity of raphe neurons when recorded in vivo. The viability of these neurons in vitro thus provides a preparation for analyzing endogenous and exogenous factors that regulate the activity of these serotonin-containing neurons.