The rising prevalence of diabetes and impaired glucose tolerance - The Australian diabetes, obesity and lifestyle study
The rising prevalence of diabetes and impaired glucose tolerance - The Australian diabetes, obesity and lifestyle study
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DOI：
10.2337/diacare.25.5.829
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发表时间：
2002-05-01
期刊：
影响因子：
16.2
通讯作者：
Shaw, JE
中科院分区：
文献类型：
--
作者：
Dunstan, DW;Zimmet, PZ;Shaw, JE
目的-确定糖尿病和其他类型葡萄糖耐受不良的人群患病率（糖耐量受损[IGT]和空腹血糖受损[IFG]），并将患病率与以前的澳大利亚数据进行比较。247名年龄大于或等于25岁的参与者生活在从六个州和北领地随机选择的42个地区，在一项横断面调查中使用75-g口服葡萄糖耐量试验，以评估空腹和2小时血浆葡萄糖浓度。世界卫生组织的诊断标准被用来确定糖耐量异常的患病率。结果-糖尿病在澳大利亚的患病率为8.0%，在Trien和6.89%的妇女，另外17.4%的男性和15.4%的女性有IGT或IFG。即使在最年轻的年龄组（25-34岁）中，也有5.7%的受试者存在糖耐量异常。澳大利亚的总体糖尿病患病率为7.4%，另有16.4%患有IGT或IFG。自1981年以来，糖尿病患病率增加了一倍多，这只是年龄分布和肥胖的变化的部分原因。结论-澳大利亚糖尿病和其他类别的糖耐量异常的患病率迅速上升。在澳大利亚，葡萄糖耐量异常的患病率是迄今为止报告的最高的一个发达国家，主要是欧洲背景。
OBJECTIVE - To determine the population-based prevalence of diabetes and other categories of glucose intolerance (Impaired glucose tolerance [IGT] and impaired fasting glucose [IFG]) in Australia and to compare the prevalence with previous Australian data.RESEARCH DESIGN AND METHODS - A national sample involving 11,247 participants aged greater than or equal to25 years living in 42 randomly selected areas from the six states and the Northern Territory were examined in a cross-sectional survey using the 75-g oral glucose tolerance test to assess fasting and 2-h plasma glucose concentrations. The World Health Organization diagnostic criteria were used to determine the prevalence of abnormal glucose tolerance.RESULTS - The prevalence of diabetes in Australia was 8.0% in Trien and 6.89% in women, and an additional 17.4% of men and 15.4% of women had IGT or IFG. Even in the youngest age group (25-34 years), 5.7% of subjects had abnormal glucose tolerance. The overall diabetes prevalence in Australia was 7.4%, and an additional 16.4% had IGT or IFG. Diabetes prevalence has more than doubled since 1981, and this is only partially explained by changes in age profile and obesityCONCLUSIONS - Australia has a rapidly rising prevalence of diabetes and other categories of abnormal glucose tolerance. The prevalence of abnormal glucose tolerance in Australia is one of the highest yet reported from a developed nation with a predominantly Europid background.