A Ratiometric Selective Fluorescent Probe Derived from Pyrene for Cu2+ Detection
A Ratiometric Selective Fluorescent Probe Derived from Pyrene for Cu2+ Detection
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DOI：
10.3390/chemosensors10060207
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发表时间：
2022-05
期刊：
影响因子：
4.2
通讯作者：
Chunwei Yu;Meiding Yang;Shuhua Cui;Yuxiang Ji;Jun Zhang
中科院分区：
文献类型：
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作者：
Chunwei Yu;Meiding Yang;Shuhua Cui;Yuxiang Ji;Jun Zhang
以芘衍生物为基础，合理构造了一种新型的比例Cu2+选择性探针。与其他被测金属离子相比，该探针对Cu2+具有选择性识别，在393 nm和415 nm处具有显著的开启荧光响应。在优化条件下，水溶液中Cu2+的检出限为0.16 μM。此外，通过质谱和Job’s plot实验证实了金属-配体配合物为1:1，并通过1H NMR实验研究了其结合模式。同时对活细胞进行荧光成像检测Cu2+，结果令人满意。
A novel ratiometric Cu2+-selective probe was rationally constructed based on pyrene derivative. Compared to other tested metal ions, the probe presented the selective recognition for Cu2+ which could be detected by a significant turn-on fluorescent response at 393 nm and 415 nm. Under the optimized conditions, a detection limit of 0.16 μM Cu2+ in aqueous media was found. Besides this, a 1:1 metal–ligand complex was confirmed by MS spectra and Job’s plot experiment, and the binding mode was also studied by 1H NMR experiment. Meanwhile, the fluorescence imaging in living cells was performed to detect Cu2+ with satisfactory results.