Identification of Bacterial and Viral Codetections With Mycoplasma pneumoniae Using the TaqMan Array Card in Patients Hospitalized With Community-Acquired Pneumonia.

Identification of Bacterial and Viral Codetections With Mycoplasma pneumoniae Using the TaqMan Array Card in Patients Hospitalized With Community-Acquired Pneumonia.
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DOI:
10.1093/ofid/ofw071
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发表时间:
2016-03
影响因子:
4.2
通讯作者:
Winchell JM
Winchell JM
中科院分区:
医学3区
文献类型:
--
作者:
Diaz MH;Cross KE;Benitez AJ;Hicks LA;Kutty P;Bramley AM;Chappell JD;Hymas W;Patel A;Qi C;Williams DJ;Arnold SR;Ampofo K;Self WH;Grijalva CG;Anderson EJ;McCullers JA;Pavia AT;Wunderink RG;Edwards KM;Jain S;Winchell JM

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在最近的一项前瞻性研究中,在许多社区获得性肺炎患者中检测到肺炎支原体。为了评估在这些患者中是否也检测到其他病原体,使用TaqMan阵列卡检测216份肺炎支原体阳性呼吸道标本中的25种其他病毒和细菌呼吸道病原体。值得注意的是,在大约60%的标本中发现了1个或多个共同检测,主要是细菌,其中共同检测在儿童中更常见。
Mycoplasma pneumoniae was detected in a number of patients with community-acquired pneumonia in a recent prospective study. To assess whether other pathogens were also detected in these patients, TaqMan Array Cards were used to test 216 M pneumoniae-positive respiratory specimens for 25 additional viral and bacterial respiratory pathogens. It is interesting to note that 1 or more codetections, predominantly bacterial, were identified in approximately 60% of specimens, with codetections being more common in children.