Comparing antibiotic self-medication in two socio-economic groups in Guatemala City: a descriptive cross-sectional study.
Comparing antibiotic self-medication in two socio-economic groups in Guatemala City: a descriptive cross-sectional study.
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DOI：
10.1186/s40360-015-0011-3
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发表时间：
2015-04-27
影响因子：
2.9
通讯作者：
Cerón A
中科院分区：
文献类型：
--
作者：
Ramay BM;Lambour P;Cerón A
自行服用抗生素可能会导致抗菌素耐药性，其高患病率在危地马拉等中低收入国家 (LMIC) 尤为令人担忧。更好地了解抗生素的自我药疗可能是制定指导合理使用抗生素的干预措施的机会。我们的目的是比较抗生素自我药疗的程度以及在危地马拉城为不同社会经济社区提供服务的两家药房中自我药疗者的特征。我们在危地马拉城的一家郊区药房和一家市中心药房进行了一项描述性横断面研究。我们使用问卷调查来收集有关自我药疗频率、自我药疗者的收入和教育程度的信息。我们酌情使用双样本 z 检验比较了两家药房的比例。 418 名受访者完成了调查（郊区药房有 221 名受访者，市中心药房有 197 名受访者）。两家药店的大多数受访者都是女性（70%）。郊区药房报告的月收入在 $1,250.00-$2,500.00 之间，市中心药房报告的月收入在 $125.00-$625.00 之间 (p < 0.01)。 23% 的郊区药房受访者和 3% 的市中心药房受访者完成了高中学业 (p<0.01)。郊区药房的自我药疗比例为 79%，市中心药房的自我药疗比例为 77%。据报道，在这两种情况下，阿莫西林都是最常用的抗生素。据报道，危地马拉城的两家为不同社会经济群体提供服务的药店中，自行服用抗生素的比例很高。此外，自我药疗的受访者最常见的是女性，并且最常见的是使用阿莫西林进行自我药疗。我们的研究结果支持未来的公共卫生干预措施，重点是抗生素销售的监管以及药剂师在危地马拉指导抗生素处方方面的潜在作用。本文的在线版本 (doi:10.1186/s40360-015-0011-3) 包含补充材料，可供授权用户使用。
Self-medication with antibiotics may result in antimicrobial resistance and its high prevalence is of particular concern in Low to Middle Income Countries (LMIC) like Guatemala. A better understanding of self-medication with antibiotics may represent an opportunity to develop interventions guiding the rational use of antibiotics. We aimed to compare the magnitude of antibiotic self-medication and the characteristics of those who self-medicate in two pharmacies serving disparate socio-economic communities in Guatemala City. We conducted a descriptive, cross-sectional study in one Suburban pharmacy and one City Center pharmacy in Guatemala City. We used a questionnaire to gather information about frequency of self-medication, income and education of those who self-medicate. We compared proportions between the two pharmacies, using two-sample z-test as appropriate. Four hundred and eighteen respondents completed the survey (221 in the Suburban pharmacy and 197 in the City Center pharmacy). Most respondents in both pharmacies were female (70%). The reported monthly income in the suburban pharmacy was between $1,250.00-$2,500.00, the city-center pharmacy reported a monthly income between $125.00- $625.00 (p < 0.01). Twenty three percent of Suburban pharmacy respondents and 3% in the City Center pharmacy completed high school (p < 0.01). Proportion of self-medication was 79% in the Suburban pharmacy and 77% in City Center pharmacy. In both settings, amoxicillin was reported as the antibiotic most commonly used. High proportions of self-medication with antibiotics were reported in two pharmacies serving disparate socio-economic groups in Guatemala City. Additionally, self-medicating respondents were most often women and most commonly self-medicated with amoxicillin. Our findings support future public health interventions centered on the regulation of antibiotic sales and on the potential role of the pharmacist in guiding prescription with antibiotics in Guatemala. The online version of this article (doi:10.1186/s40360-015-0011-3) contains supplementary material, which is available to authorized users.
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