Cretinism with goiter; a case report.
Cretinism with goiter; a case report.
复制标题
克汀病伴甲状腺肿；
DOI：
10.1210/jcem-11-7-740
复制
发表时间：
1951
期刊：
影响因子：
--
通讯作者：
J. Stanbury
中科院分区：
文献类型：
--
作者：
J. Stanbury
患有甲状腺肿的克汀病患者可表现出放射性碘的高积累。在对3名这样的兄弟姐妹（1）进行的研究中，发现在给予硫氰酸钾后，放射性碘迅速从甲状腺排出，这一观察结果被解释为这些患者的甲状腺无法将碘结合到蛋白质复合物中。本病例报告涉及另一种甲状腺肿性克汀病，由C。D.波士顿儿童医院的库克雪莉·O MGH #696322是一名13岁的女性，据说出生时头部较大，有脐疝。在五个月大的时候，因为没有增加，喂养不良，嗜睡和便秘，诊断为克汀病。她被给予干燥的甲状腺，剂量每天高达2格令。她很快就有了进步，但直到2岁才开始走路，3岁才开始说话。智力迟钝总是很明显的。一年前，她的父母没有...
CRETINOUS patients with goiter may show a high accumulation of radioactive iodine. In studies on 3 such siblings (1) the radioactive iodine was found to be rapidly discharged from the thyroid upon the administration of potassium thiocyanate, an observation which was interpreted to mean that the thyroid glands of these patients were unable to incorporate iodide into a protein complex. This case report concerns another goitrous cretin, referred by Dr. C. D. Cook of the Children's Hospital of Boston. Shirley O., MGH #696322 a 13-year-old female, was said to have had a large head and an umbilical hernia at birth. At five months of age because of failure to gain, poor feeding, drowsiness and constipation, a diagnosis of cretinism was made. She was given desiccated thyroid in dosages varying up to 2 grains daily. Prompt improvement followed, but she did not walk until she was 2 and began to talk only when she reached the age of 3. Mental retardation was always evident. One year before admission her parents noti...