Hepatic interferon‐gamma‐induced protein‐10 expression is more strongly associated with liver fibrosis than interleukin‐28B single nucleotide polymorphisms in hepatocellular carcinoma resected patients with chronic hepatitis C
Hepatic interferon‐gamma‐induced protein‐10 expression is more strongly associated with liver fibrosis than interleukin‐28B single nucleotide polymorphisms in hepatocellular carcinoma resected patients with chronic hepatitis C
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DOI：
10.1111/hepr.12070
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发表时间：
2013-11
影响因子：
4.2
通讯作者：
H. Konishi;K. Shirabe;S. Yoshiya;T. Ikeda;T. Ikegami;T. Yoshizumi;Ayae Ikawa-Yoshida;T. Motomura;T. Fukuhara;Y. Maehara
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文献类型：
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作者：
H. Konishi;K. Shirabe;S. Yoshiya;T. Ikeda;T. Ikegami;T. Yoshizumi;Ayae Ikawa-Yoshida;T. Motomura;T. Fukuhara;Y. Maehara
IL - 28B周围的单核苷酸多态性（SNP）和干扰素（IFN）刺激基因（ISG）表达是慢性丙型肝炎病毒（HCV）感染对IFN标准治疗反应的预测因子。我们分析了这些预测因子之间的相关性，以提高对肝细胞癌（HCC）肝切除术后IFN治疗反应的预测。
Single nucleotide polymorphisms (SNP) around IL‐28B and interferon (IFN)‐stimulated gene (ISG) expression are predictors of response to standard therapy involving IFN for chronic hepatitis C virus (HCV) infection. We analyzed the association between these predictors to improve the prediction of the response to IFN therapy after liver resection for hepatocellular carcinoma (HCC).