Synthesis of multisubstituted N-(tosylamino)pyrrole derivatives by AuCl3-catalyzed cycloisomerization of the beta-alkynyl hydrazones
Synthesis of multisubstituted N-(tosylamino)pyrrole derivatives by AuCl3-catalyzed cycloisomerization of the beta-alkynyl hydrazones
复制标题
AuCl3 催化 β-炔基腙环异构化合成多取代 N-(甲苯磺酰氨基)吡咯衍生物
DOI：
10.1080/00397911.2016.1205626
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发表时间：
2016
影响因子：
2.1
通讯作者：
You Jinmao
中科院分区：
文献类型：
--
作者：
Cao Ziping;Zhu Hongbo;Meng Xin;Li Jie;Li Shan;Huang Zihao;Zhu Jiekun;Sun Xuejun;You Jinmao
报道了一种以AuCl 3为催化剂，β-炔基腙类化合物为原料，环化异构化制备多取代N-（对甲苯磺酰氨基）吡咯衍生物的方法。该反应可以从β-酮酯在一锅中进行，以中等至优异的产率得到环化产物，催化剂负载量低。
A method for preparing multisubstitutedN-(tosylamino)pyrrole derivatives through AuCl3-catalyzed cycloisomerization of the β-alkynyl hydrazone compounds was described. The reaction could be carried out in one pot from the β-ketoesters to give the cyclized products in moderate to excellent yields with low catalyst loadings.