USE OF MEDICAID DATA FOR PHARMACOEPIDEMIOLOGY

USE OF MEDICAID DATA FOR PHARMACOEPIDEMIOLOGY
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DOI:
10.1093/oxfordjournals.aje.a115198
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发表时间:
1989-04-01
影响因子:
5
通讯作者:
GRIFFIN, MR
GRIFFIN, MR
中科院分区:
医学2区
文献类型:
--
作者:
RAY, WA;GRIFFIN, MR

文献摘要

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由于处方药使用的高流行率和许可时对药物作用的不完全理解,需要进行持续的流行病学监测,为临床和监管决策提供信息。通过医疗补助计划的管理产生的数据已被考虑用于此目的,因为计算机化的文件包括处方和诊断信息的大,定义的人群。然而,计算机化文件中可用的数据量有限,医疗补助人群的非典型人口统计学特征给药物流行病学使用这些数据带来了巨大的困难。本文回顾了这些方法的问题,并介绍了务实的解决方案,已通过正在进行的使用这些数据库的流行病学研究。
Because of the high prevalence of prescription drug use and the incomplete understanding of drug effects at the time of licensing, ongoing epidemiologic monitoring is required to provide information for clinical and regulatory decisions. Data produced through the administration of Medicaid programs have been considered for this purpose because the computerized files include prescription and diagnostic information for large, defined populations. However, the limited amount of data available in the computerized files and the atypical demographic characteristics of Medicaid populations create formidable difficulties in the use of these data for pharmacoepidemiology. This paper reviews these methodological problems and describes pragmatic solutions that have been developed through the ongoing use of these data bases for epidemiologic studies.