Detection of early-stage lung cancer: Computed tomography scan or chest radiograph?
Detection of early-stage lung cancer: Computed tomography scan or chest radiograph?
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DOI：
10.1067/mtc.2001.112827
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发表时间：
2001-06-01
影响因子：
6
通讯作者：
Pasmantier, M
中科院分区：
文献类型：
--
作者：
Altorki, N;Kent, M;Pasmantier, M
目的：CT是一种早期发现肺癌的有效方法。在这项研究中，我们比较了计算机断层扫描和常规胸部X线片发现的肺癌的分期分布。方法：回顾两组经活检证实的非小细胞肺癌患者。在第一组32名患者中，肿瘤是通过计算机断层扫描发现的。第二组(n=101)在常规胸片上发现肺癌。有肺部症状或癌症病史的患者被排除在外。结果：两组患者在年龄、性别或细胞类型分布上没有差异。与那些接受X光胶片扫描的患者相比，接受计算机断层扫描的患者中患IA期疾病的人数明显更多。在接受扫描的32名患者中，10名肿瘤大小在1厘米或更小，而接受胸部X光检查的101名患者中有6名。结论：在这项回顾性研究中，接受计算机断层扫描的患者的IA期肺癌的发生率高于胸部X线片的患者，而晚期肺癌的病例明显少于胸部X线片的患者。这些数据表明，计算机断层扫描可能对提高非小细胞肺癌患者的存活率有价值。
Objective: Computed tomography has recently been proposed as a useful method for the early detection of lung cancer. In this study we compared the stage distribution of lung cancers detected by a computed tomographic scan with that of lung cancers detected by a routine chest x-ray film.Methods: Two groups of patients with biopsy-proven non-small cell lung cancer were reviewed. In the first group of 32 patients, the tumors were detected by a computed tomographic scan. In a second group (n = 101), the lung cancers were detected on routine chest x-ray films. Patients with pulmonary symptoms or a history of cancer were excluded.Results: There was no difference in age, sex, or cell-type distribution between the 2 groups. A significantly greater number of patients undergoing a computed tomographic scan had stage IA disease compared with those having an x-ray film. Of the 32 patients in the group having a scan, 10 had tumors 1 cm or less in size versus 6 of 101 in the group having a chest radiograph. Additionally, there was a significant reduction in advanced stage disease in the group having a scan.Conclusions: In this retrospective study, a higher incidence of stage IA lung cancers and significantly fewer cases of more advanced disease were observed in patients screened with computed tomography than in those having chest radiograph. These data suggest that computed tomographic screening may be of value in improving the survival of patients with non-small cell lung cancer.