Low birth weight and dental fluorosis: is there an association?
Low birth weight and dental fluorosis: is there an association?
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低出生体重和氟斑牙：有关联吗？
DOI：
10.1111/j.1752-7325.2000.tb03323.x
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发表时间：
2000
影响因子：
2.3
通讯作者：
Swango,PA
中科院分区：
文献类型：
--
作者：
Kumar,JV;Swango,PA
目的：通过横断面研究探讨低出生体重与氟斑牙之间的关联，以解释非裔美国儿童氟斑牙患病率较高。方法：从纽约州出生登记处获得 960 名儿童的出生体重数据。在纽堡和金斯顿进行的一项横断面研究提供了有关种族、氟化物暴露、社会人口特征和氟斑牙的数据。使用逻辑回归程序探讨了出生体重、种族和氟化水氟化物暴露、定期使用补充剂、2岁前刷牙和受试者水平氟斑牙之间的关联。结果：与低出生体重、种族和氟化物暴露相关的主效应和双向交互效应的回归系数不具有统计学显着性。即使在控制了低出生体重和氟化物暴露之后，非洲裔美国儿童的比值比在统计学上也显着较高（OR=2.0）。对仅限于下颌第一恒磨牙的数据的分析显示出类似的效果，除了接触氟化物补充剂的低出生体重儿童的效果改变的证据之外。结论：较低的出生体重并不能解释在非洲裔美国儿童中观察到的氟斑牙患病率较高。
Objective: The association between low birth weight and dental fluorosis was explored in a cross‐sectional study to explain the higher prevalence of dental fluorosis among African‐American children.Methods: Birth weight data on 960 children were obtained from the New York State Birth Registry. Data on race, fluoride exposure, sociodemographic characteristics, and dental fluorosis were available from a cross‐sectional study conducted in Newburgh and Kingston. Associations among birth weight, race, and fluoride exposure from fluoridated water, regular use of supplements, brushing before the age of 2 years, and subject‐level dental fluorosis were explored using logistic regression procedures.Results: The regression coefficients for the main effects and the two‐way interaction effects associated with low birth weight, race, and fluoride exposure were not statistically significant. Even after controlling for low birth weight and fluoride exposure, African‐American children had a statistically significant higher odds ratio (OR=2.0). An analysis of the data limited to mandibular permanent first molars showed similar effects, except for evidence of effect modification in low birth weight children exposed to fluoride supplements.Conclusions: Lower birth weight did not explain the higher prevalence of dental fluorosis observed among African‐American children.