Clinical therapeutic effects of gastrodin in combination with betahistine on vertigo: A protocol for systematic review and meta-analysis.
Clinical therapeutic effects of gastrodin in combination with betahistine on vertigo: A protocol for systematic review and meta-analysis.
复制标题
天麻素联合倍他司汀治疗眩晕的临床疗效：系统评价和荟萃分析方案。
DOI：
10.1097/md.0000000000023825
复制
发表时间：
2021-03-12
期刊：
影响因子：
1.6
通讯作者：
Jin S
中科院分区：
文献类型：
--
作者：
Qiao YL;Xiang WQ;Liu F;Jin S
眩晕是一种众所周知的主诉，常见于主要护理办公室和科室。它也被认为是前庭功能障碍的症状，并被表达为运动感觉，特别是旋转运动。随着患者年龄的增长，眩晕也成为常见的主诉。目前的研究将进行广泛的系统评价，以评估天麻素联合倍他司汀治疗眩晕的临床疗效。我们将系统地检索不同的数据库，包括PubMed、EMBASE、Web of Science、Cochrane图书馆、中国生物医学文献数据库（CBM）、中国知网（CNKI）和万方数据库，收集自成立以来至2020年11月评估天麻素和倍他司汀治疗眩晕患者疗效的随机对照研究。但仅纳入英文或中文研究。两位作者将独立对纳入的论文进行选择、数据提取和偏倚风险评估。因此，独立作者之间的任何分歧将通过讨论或在需要时咨询第三作者来解决。此外，我们将使用 RevMan 5.3 软件来执行数据合成。将系统评估天麻素和倍他司汀治疗眩晕患者的疗效。本研究旨在为探索天麻素联合倍他司汀治疗眩晕是否更有效提供更一致的证据。 DOI 10.17605/OSF.IO/HQTZA (https://osf.io/hqtza/)
Vertigo is a well-known presenting complaint common in the main care offices as well as departments. It is also regarded as a symptom of vestibular dysfunction and has been expressed as a feeling of motion, specifically rotational motion. As patients grow older, vertigo also becomes a commonly presenting complaint. The current study will carry out a widespread systematic review to estimate clinical therapeutic effects of gastrodin in combination with betahistine on vertigo. We will systematically search different databases, including PubMed, EMBASE, Web of Science, the Cochrane Library, Chinese BioMedical Literature Database (CBM), China National Knowledge Infrastructure Database (CNKI), and WanFang to collect the randomised controlled studies that evaluate the efficiency of gastrodin and betahistine in treating patients with vertigo from their inception to November 2020. However, only studies in English or Chinese will be included. Two authors will independently perform selection, data extraction, and assessment of risk of bias for the included papers. Accordingly, any disagreements between the independent authors will be addressed via discussion or by consulting a third author when needful. Additionally, we will use RevMan 5.3 software to perform the data synthesis. The efficiency of gastrodin and betahistine in treating patients with vertigo will be systematically evaluated. The current study aims to stipulate more consistent substantiation to explore whether gastrodin combined with betahistine is more effective for the treatment of vertigo. DOI 10.17605/OSF.IO/HQTZA (https://osf.io/hqtza/)