Nonintrusive Vital Signs Monitoring for Sleep Apnea Patients: A Preliminary Study
Nonintrusive Vital Signs Monitoring for Sleep Apnea Patients: A Preliminary Study
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DOI：
10.1109/access.2017.2783939
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发表时间：
2018-01-01
期刊：
影响因子：
3.9
通讯作者：
Mokhtari, Mounir
中科院分区：
文献类型：
--
作者：
Sadek, Ibrahim;Seet, Edwin;Mokhtari, Mounir
睡眠是一种基本的和重要的生理功能。获得足够的高质量睡眠对一个人的心理健康，生理健康，生活质量和安全是必要的。睡眠呼吸障碍，特别是阻塞性睡眠呼吸暂停，会导致严重的健康问题，包括高血压和中风。目前用于诊断睡眠障碍的方法是繁琐的、侵入性的，并且可以影响患者的睡眠质量。因此，迫切需要一种不那么笨重的系统来诊断与睡眠有关的问题。在本文中，我们评估的能力的微弯光纤传感器监测心率和呼吸的非侵入性方式。此外，我们测试了传感器在浅呼吸和无呼吸之间的区分能力。在药物诱导睡眠内窥镜检查期间，在临床环境中将所提出的传感器与三通道便携式监测设备（ApneaLink）进行了比较。在我们研究招募的所有10名患者中，该系统在平均心率和平均呼吸率方面取得了令人满意的结果，误差分别为0.55 +/- 0.59次/分钟和0.38 +/- 0.32次/分钟。此外，对于心率和呼吸，所提出的传感器和参考设备之间的Pearson相关系数分别为0.96和0.78。相反，所提出的传感器对于睡眠呼吸暂停检测提供了非常低的灵敏度（24.24 +/- 12.81%）和相对高的特异性（85.88 +/- 6.01%）。预计这项初步研究将为真实的时间内不引人注目地检测生命体征铺平道路。
Sleep is a fundamental and vital physiological function. Getting enough quality sleep is necessary to a person's mental health, physiological well-being, quality of life, and safety. Sleep-disordered breathing, specifically obstructive sleep apnea can result in serious health issues, including hypertension and stroke. The current approaches for diagnosing sleep disorders are burdensome, intrusive, and can affect the patient's sleep quality. As a result, there is a crucial need for less cumbersome systems to diagnose sleep-related problems. In this paper, we evaluated the capacity of the microbend fiber optic sensor to monitor heart rate and respiration in a nonintrusive manner. In addition, we tested the capacity of the sensor in discriminating between shallow breathing and no breathing. The proposed sensor was compared with the three-channel portable monitoring device (ApneaLink) in a clinical setting during a drug-induced sleep endoscopy. Across all ten patients recruited for our study, the system achieved satisfactory results in the mean heart rate and the mean respiratory rate with an error of 0.55 +/- 0.59 beats/minute and 0.38 +/- 0.32 breaths/minute, respectively. Besides, the Pearson correlation coefficient between the proposed sensor and the reference device was 0.96 and 0.78 for heart rate and respiration, respectively. On the contrary, the proposed sensor provided a very low sensitivity (24.24 +/- 12.81%) and a relatively high specificity (85.88 +/- 6.01%) for sleep apnea detection. It is expected that this preliminary research will pave the way toward unobtrusive detection of vital signs in real time.