Clinical characteristics and outcomes of septic patients with new-onset atrial fibrillation
Clinical characteristics and outcomes of septic patients with new-onset atrial fibrillation
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DOI：
10.1016/j.jcrc.2007.09.005
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发表时间：
2008-12-01
影响因子：
3.7
通讯作者：
Gerber, David R.
中科院分区：
文献类型：
--
作者：
Christian, Sangita-Ann;Schorr, Christa;Gerber, David R.
Purpose: No studies have specifically evaluated the incidence or clinical characteristics of atrial fibrillation (AF) in a mixed medical-surgical population of patients with sepsis. We undertook to determine the incidence and clinical Course of critically ill septic patients in the intensive care unit (ICU) who developed new-onset AF.Methods: Retrospective analysis of data collected from the Project IMPACT database on 274 septic patients from July 2003 to December 2004.Results: Sixteen evaluable septic patients with new-onset AF were identified. Mortality was higher (P = .034) and ICU length of stay (LOS) longer (P = .003) in patients with AF vs those without. Intensive care unit LOS was also longer in the subset of survivors with AF (P = .0001). Hospital LOS was longer among survivors with AF than in survivors without AF (P = .047). patients with AF had a greater need for mechanical ventilation (P = .0007). Survivors with AF had longer duration of mechanical ventilation than those without AF (P = .006).Conclusions: Statistically significantly higher mortality was observed in critically ill septic patients with new-onset AF, as were longer duration of mechanical ventilation, ICU, and hospital LOS. Whether the higher incidence of AF in septic patients is a specific risk factor for outcome or an indication of severity of illness remains to be determined. (c) 2008 Elsevier Inc. All rights reserved.
