Pleural Malignancies
Pleural Malignancies
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DOI：
10.1016/j.semradonc.2010.01.009
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发表时间：
2010-07-01
影响因子：
3.5
通讯作者：
Cengel, Keith A.
中科院分区：
文献类型：
--
作者：
Friedberg, Joseph S.;Cengel, Keith A.
胸膜恶性肿瘤，原发或转移，预示着一个严峻的预后。除了严重的肿瘤学意义的胸膜恶性肿瘤，这些肿瘤可高度症状。恶性胸腔积液可引起呼吸困难，继发于肺压迫，甚至是压力下胸水引起的紧张生理。缓解这些积液的需要似乎是一个直截了当地的临床场景，但如果处理不当，细微差别可能会导致灾难性的并发症。实性胸膜恶性肿瘤可因侵犯胸壁而引起剧烈疼痛，或因侵犯胸壁结构（如心脏、肺或食道）而引起各种病态症状。这篇文章回顾了胸膜恶性肿瘤，纯粹姑息性治疗，和治疗是执行明确（治愈）的意图。中国生物医学工程学报（英文版），20(5):559 - 564。版权所有。
Pleural malignancies, primary or metastatic, portend a grim prognosis. In addition to the serious oncologic implications of a pleural malignancy, these tumors can be highly symptomatic. A malignant pleural effusion can cause dyspnea, secondary to lung compression, or even tension physiology from a hydrothorax under pressure. The need to palliate these effusions is a seemingly straightforward clinical scenario, but with nuances that can result in disastrous complications for the patient if not attended to appropriately. Solid pleural malignancies can cause great pain from chest wall invasion or can cause a myriad of morbid symptoms because of the invasion of thoracic structures, such as the heart, lungs, or esophagus. This article reviews pleural malignancies, the purely palliative treatments, and the treatments that are performed with definitive (curative) intent. Semin Radiat Oncol 20:208-214 (C) 2010 Elsevier Inc. All rights reserved.