Burden of heart failure and underlying causes in 195 countries and territories from 1990 to 2017
Burden of heart failure and underlying causes in 195 countries and territories from 1990 to 2017
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DOI：
10.1093/eurjpc/zwaa147
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发表时间：
2021-02-12
影响因子：
8.3
通讯作者：
Dai, Haijiang
中科院分区：
文献类型：
--
作者：
Bragazzi, Nicola Luigi;Zhong, Wen;Dai, Haijiang
目的提供1990年至2017年195个国家和地区心力衰竭（HF）负担和潜在原因的首次系统分析。方法和结果我们从2017年全球疾病负担研究中收集了有关HF患病率、残疾生活年数（YLD）和潜在原因的详细信息。按年龄、性别、社会人口统计学指数（SDI）和地点比较HF患病率和YLD的数量和年龄标准化率。还列出了由23种潜在原因引起的HF年龄标准化患病率的比例。在全球范围内，2017年HF的年龄标准化患病率和YLD率分别为831.0/10万人和128.2/10万人，分别比1990年下降了-7.2%和-0.9%。然而，从1990年开始，HF流行病例和YLD的绝对数分别增加了91.9%和106.0%。从1990年到2017年，HF负担的水平和趋势存在显著的地理和社会人口统计学差异。2017年，在所有HF病因中，缺血性心脏病占HF年龄标化患病率的比例最高（26.5%），其次是高血压性心脏病（26.2%），慢性阻塞性肺疾病（23.4%）。结论HF仍是全球严重的公共卫生问题，在SDI相对较低的国家，年龄标化患病率和YLD率不断上升。旨在预防HF的根本原因和改善HF的医疗护理的更具地域特异性的策略是必要的，以减少这种情况的未来负担。
Aims To provide the first systematic analysis of the burden and underlying causes of heart failure (HF) in 195 countries and territories from 1990 to 2017.Methods and results We collected detailed information on prevalence, years lived with disability (YLDs), and underlying causes of HF from the Global Burden of Disease study 2017. Numbers and age-standardized rates of HF prevalence and YLDs were compared by age, sex, socio-demographic index (SDI), and location. The proportions of HF age-standardized prevalence rates due to 23 underlying causes were also presented. Globally, the age-standardized prevalence and YLD rates of HF in 2017 were 831.0 and 128.2 per 100 000 people, a decrease of -7.2% and -0.9% from 1990, respectively. Nevertheless, the absolute numbers of HF prevalent cases and YLDs have increased by 91.9% and 106.0% from 1990, respectively. There is significant geographic and socio-demographic variation in the levels and trends of HF burden from 1990 to 2017. Among all causes of HF, ischaemic heart disease accounted for the highest proportion (26.5%) of age-standardized prevalence rate of HF in 2017, followed by hypertensive heart disease (26.2%), chronic obstructive pulmonary disease (23.4%).Conclusion HF remains a serious public health problem worldwide, with increasing age-standardized prevalence and YLD rates in countries with relatively low SDI. More geo-specific strategies aimed at preventing underlying causes and improving medical care for HF are warranted to reduce the future burden of this condition.