A chemical reporter strategy to probe glycoprotein fucosylation
A chemical reporter strategy to probe glycoprotein fucosylation
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DOI：
10.1021/ja064619y
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发表时间：
2006-09-20
影响因子：
15
通讯作者：
Bertozzi, Carolyn R.
中科院分区：
文献类型：
--
作者：
Rabuka, David;Hubbard, Sarah C.;Bertozzi, Carolyn R.
聚焦糖蛋白参与许多细胞-细胞识别事件，是胚胎组织和恶性组织的标志物。在这里，我们报告了一种快速分析人类细胞聚焦糖蛋白的方法，使用6-叠氮聚焦作为代谢标记。
Fucosylated glycoproteins are involved in many cell−cell recognition events and are markers of embryonic and malignant tissue. Here we report a method for rapid profiling of fucosylated glycoproteins from human cells using 6-azido fucose as a metabolic label.