The contribution of pain, reported sleep quality, and depressive symptoms to fatigue in fibromyalgia
The contribution of pain, reported sleep quality, and depressive symptoms to fatigue in fibromyalgia
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DOI：
10.1016/s0304-3959(02)00300-7
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发表时间：
2002-12-01
期刊：
影响因子：
7.4
通讯作者：
Gevirtz, RN
中科院分区：
文献类型：
--
作者：
Nicassio, PM;Moxham, EG;Gevirtz, RN
本研究的主要目的是评估纤维肌痛(FM)患者疲劳的预测因素。使用横断面和每日评估方法，在横断面阶段的研究中，涉及105名FM患者样本。更大的抑郁和更低的睡眠质量同时伴随着更高的疲劳感。而疼痛与疲劳是相关的。在回归方程中，它对疲劳没有独立的贡献。对于横断面样本(n=63)中的一组患者，他们参加了一周的前瞻性每日疼痛评估。睡眠质量和疲劳，每日总分(平均)的多元回归分析表明，前一天的疼痛和睡眠质量预测第二天的疲劳。横断期的抑郁与每日累积的疲劳评分无关。路径分析框架被测试，用分类(去除受试者之间的变异性)数据，其中疼痛被预测为对加载者睡眠质量的贡献。反过来。正如预测的那样，X会导致更大的疲劳。结果表明，睡眠质量差完全解释了疼痛和疲劳之间的正相关关系，从而证实了睡眠质量的中介作用。这些发现表明，这是一种功能失调。剧烈疼痛和不安宁睡眠的周期性模式是FM疲劳体验的基础。(C)2002年国际疼痛研究协会。爱思唯尔科学公司出版。版权所有。
The major objective of this research was to evaluate the predictors of fatigue in patients with fibromyalgia (FM). using cross-sectional and daily assessment methodologies, In the cross-sectional phase of the research involving a sample of 105 FM patients. greater depression and lower sleep quality A ere concurrently associated with higher fatigue. While pain was correlated with fatigue. it did not independently contribute to fatigue in the regression equation. For a subset of patients from the cross-sectional sample (n = 63) who participated in a week of prospective daily assessment of their pain. sleep quality and fatigue, multiple regression analysis of aggregated (averaged) daily scores revealed that previous day's pain and sleep quality predicted next day's fatigue. Depression from the cross-sectional phase was not related to aggregated daily fatigue scores. A path analytic framework was tested, with disaggregated (removing between subjects variability) data in which pain was predicted to contribute to loader sleep quality which. in turn. x as predicted to lead to greater fatigue. The results revealed that poor sleep quality fully accounted for the positive relationship between pain and fatigue, thus substantiating the mediational role of sleep quality. The findings are indicative of a dysfunctional. cyclical pattern of heightened pain and non-restful sleep underlying the experience of fatigue in FM. (C) 2002 International Association for the Study of Pain. Published by Elsevier Science B.V. All rights reserved.