START smuggling CoQ to fight ferroptosis.
START smuggling CoQ to fight ferroptosis.
复制标题
开始走私 CoQ 来对抗铁死亡。
DOI:
10.1038/s41556-022-01044-1
复制
发表时间:
2023
影响因子:
21.3
通讯作者:
Jiang,Xuejun
中科院分区:
文献类型:
--
作者:
Liang,Deguang;Jiang,Xuejun
Extramitochondrial coenzyme Q (CoQ) can function as a potent anti-ferroptosis radical trapper. However, it is largely unknown how CoQ is transported from mitochondria to the plasma membrane. A study now suggests that PARL-mediated STARD7 processing is responsible for the cellular distribution of CoQ.