Neurologic complications of Semple‐type rabies vaccine
Neurologic complications of Semple‐type rabies vaccine
复制标题
Semple型狂犬病疫苗的神经系统并发症
作者：
T. Hemachudha;P. Phanuphak;R. Johnson;D. Griffin;J. Ratanavongsiri;W. Siriprasomsup
我们研究了61例Semple型狂犬病疫苗接种后并发症的患者。36例有神经系统症状，25例仅有发热、头痛或肌痛。32例患者发生CNS并发症，4例发生急性周围神经病变。33例患者为急性和单相，但3例患者出现疾病进展，包括1例复发缓解期患者。没有临床特征，包括脑脊液髓鞘碱性蛋白含量，是预后指标。6例脑脊髓炎患者中有3例淋巴细胞对髓磷脂有增殖反应。
We studied 61 patients with complications of Semple-type postexposure rabies immunization. Thirty-six had neurologic signs, and 25 had only fever, headache, or myalgia. Thirty-two patients had CNS complications, and 4 had an acute peripheral neuropathy. Disease was acute and monophasic in 33, but 3 patients had progressive disease, including 1 patient with a relapsing-remitting course. No clinical features, including CSF content of myelin basic protein, were prognostic indicators. In three of six patients with encephalomyelitis, lymphocytes showed a proliferative response to myelin.