Ruthenium carbonyl-complex catalyzed hydroaminomethylation of olefins with carbon dioxide and amines
Ruthenium carbonyl-complex catalyzed hydroaminomethylation of olefins with carbon dioxide and amines
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DOI：
10.1016/j.catcom.2009.05.019
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发表时间：
2009-08
影响因子：
3.7
通讯作者：
V. Srivastava;P. Eilbracht
中科院分区：
文献类型：
--
作者：
V. Srivastava;P. Eilbracht
使用二氧化碳作为反应物，而不是有毒的一氧化碳的氢氨甲基化反应序列中首次证明。目前Ru3（CO）12催化的一锅法包括逆水煤气变换（RWGS）反应、加氢反应和还原胺化，最终得到仲胺和叔胺。考察了催化剂和相转移催化剂对反应的影响。最后，通过抑制主要副产物，以优异的产率（高达98%）具有多种胺，找到了最佳的反应条件。
Use of carbon dioxide as a reactant instead of toxic carbon monoxide in the hydroaminomethylation reaction sequence is demonstrated for the first time. The present Ru3(CO)12-catalyzed one-pot protocol includes reverse-water–gas-shift (RWGS) reaction, hydroformylation reaction and reductive amination which finally leads to secondary and tertiary amine. The influence of various reaction parameters including the effects of catalytic promotors and phase-transfer-catalysts has been investigated. Finally, an optimum reaction conditions were found by suppressing the major side products to have a variety of amines in excellent yields (up to 98%).