Melatonin and its Effects in Fishes: An Overview
Melatonin and its Effects in Fishes: An Overview
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褪黑激素及其对鱼类的影响：概述
DOI：
10.1007/978-1-4615-3042-8_12
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发表时间：
1992
期刊：
影响因子：
--
通讯作者：
J. Falcón
中科院分区：
文献类型：
--
作者：
A. Zachmann;M. Ather Ali;J. Falcón
松果体是所有脊椎动物的普遍特征，最早由盖伦（公元130-200年）记载。自从希腊解剖学家观察到松果体是大脑中一个不成对的结构以来，它一直是一个有兴趣和推测2000多年的主题。法国哲学家笛卡尔提出了这个器官在大脑功能中的重要作用，并将其视为灵魂的“右手”（源自Zrenner， 1985）。在20世纪初，首次实验表明，松果体器官参与调节生殖和低等脊椎动物的皮肤色素沉着，并对光刺激作出反应。1958年，Lerner和他的同事从牛松果体中分离出褪黑激素，开启了松果体研究的现代时代（Lerner et al., 1958）。松果体器官现在被认为是脊椎动物昼夜节律系统的一个组成部分，被认为与节律功能和行为的定时和控制有关（Hastings et al., 1989）。这似乎与松果体器官将环境刺激（主要是光周期信息）转化为神经和激素信号的能力有关。在激素信号中，吲哚酰胺褪黑激素被认为是脊椎动物体内的“授时因子”（Armstrong, 1989; Falcon and Collin, 1989; Underwood, 1989）。
The pineal gland is an universal feature of all vertebrates and was documented first by Galen (130–200 AD). It has been a subject of interest and speculation for more than 2000 years, since Greek anatomists observed that the pineal gland is an unpaired structure in the brain. The French philosopher Descartes proposed an important role for this organ in brain function and regarded it as the “right hand” of the soul (after Zrenner, 1985). At the beginning of the 20th century, first experiments indicated that the pineal organ is involved in the regulation of reproduction and skin pigmentation in lower vertebrates and responds to light stimuli. In 1958, Lerner and his coworkers were able to isolate melatonin from bovine pineals, initiating the modern era of pineal research (Lerner et al., 1958). The pineal organ is now considered as a component of the circadian system in vertebrates, and is thought to be involved in the timing and control of rhythmic functions and behaviours (Hastings et al., 1989). This seems to be related to the ability of the pineal organ to transform environmental stimuli, mainly photoperiodic information, into nervous and hormonal signals. Among the hormonal signals, the indoleamide melatonin is considered to be an internal “Zeitgeber” in vertebrates (Armstrong, 1989; Falcon and Collin, 1989; Underwood, 1989).
在昼夜照明或持续黑暗的条件下，检查灌输鳟鱼（Salmo gairdneri）松果体器官的体外褪黑激素分泌情况。
影响因子：
2.7
作者：
Gern,WA;Greenhouse,SS
通讯作者：
Greenhouse,SS