Relationship between Risk Factor Control and Compliance with a Lifestyle Modification Program in the Stenting Aggressive Medical Management for Prevention of Recurrent Stroke in Intracranial Stenosis Trial.
Relationship between Risk Factor Control and Compliance with a Lifestyle Modification Program in the Stenting Aggressive Medical Management for Prevention of Recurrent Stroke in Intracranial Stenosis Trial.
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在颅内狭窄试验中预防卒中复发的支架置入积极医疗管理中风险因素控制与生活方式改变计划依从性之间的关系。
DOI：
10.1016/j.jstrokecerebrovasdis.2017.10.017
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
SAMMPRISInvestigators
中科院分区：
文献类型：
--
作者：
Turan,TanyaN;AlKasab,Sami;Nizam,Azhar;Lynn,MichaelJ;Harrell,Jamie;Derdeyn,ColinP;Fiorella,David;Janis,LScott;Lane,BethanyF;Montgomery,Jean;Chimowitz,MarcI;SAMMPRISInvestigators
背景生活方式改变项目已经在各种临床环境中改善了危险因素目标的实现，包括先前患有中风或短暂性脑缺血发作的患者以及具有多种危险因素的患者。支架植入积极的医疗管理预防颅内狭窄复发性卒中（SAMMPRIS）是第一个血管疾病预防试验，提供了一个商业化的生活方式改变计划，以加强风险因素控制。我们试图确定遵守这一计划和危险因素控制之间的关系，在SAMMPRIS。MethodsSAMMPRIS积极的医疗管理包括一个电话的生活方式的修改程序免费提供给所有受试者（n = 451）在他们参与研究。少于3次预期生活方式指导电话的受试者从这些分析中排除。依从受试者（n = 201）的呼叫率大于或等于78.5%（完成/预期呼叫的中位数%）。不依从受试者（n = 200）的电话呼叫率低于78.5%或拒绝参与。使用t检验和卡方检验比较依从性与非依从性受试者的平均风险因子值或每个风险因子的目标百分比。从基线到随访的风险因素的变化进行了比较，占基线differentiation.ResultsCompliant受试者有更好的风险因素控制整个后续的低密度脂蛋白，收缩压（SBP），血红蛋白A1 c（HgA 1c），非高密度脂蛋白，不吸烟，运动比不合规的受试者，但没有差异的体重指数。调整组间的基线差异后，依从性的受试者有一个更大的变化，从基线比不依从性的受试者收缩压在24个月和HgA 1c在6 months.ConclusionSAMMPRIS受试者谁是符合生活方式改变计划有更好的风险因素控制在研究过程中几乎所有的风险因素。
BackgroundLifestyle modification programs have improved the achievement of risk factor targets in a variety of clinical settings, including patients who have previously suffered a stroke or transient ischemic attack and those with multiple risk factors. Stenting Aggressive Medical Management for Prevention of Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) was the first vascular disease prevention trial to provide a commercially available lifestyle modification program to enhance risk factor control. We sought to determine the relationship between compliance with this program and risk factor control in SAMMPRIS.MethodsSAMMPRIS aggressive medical management included a telephonic lifestyle modification program provided free of charge to all subjects (n = 451) during their participation in the study. Subjects with fewer than 3 expected lifestyle-coaching calls were excluded from these analyses. Compliant subjects (n = 201) had greater than or equal to 78.5% of calls (median % of completed/expected calls). Noncompliant subjects (n = 200) had less than 78.5% of calls or refused to participate. Mean risk factor values or % in-target for each risk factor was compared between compliant versus noncompliant subjects, usingttests and chi-square tests. Risk factor changes from baseline to follow-up were compared between the groups to account for baseline differences.ResultsCompliant subjects had better risk factor control throughout follow-up for low-density lipoprotein, systolic blood pressure (SBP), hemoglobin A1c (HgA1c), non–high-density lipoprotein, nonsmoking, and exercise than noncompliant subjects, but there was no difference for body mass index. After adjusting for baseline differences between the groups, compliant subjects had a greater change from baseline than noncompliant subjects for SBP did at 24 months and HgA1c at 6 months.ConclusionSAMMPRIS subjects who were compliant with the lifestyle modification program had better risk factor control during the study for almost all risk factors.
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DOI：
10.1161/circoutcomes.112.966911
发表时间：
2012-09-01
期刊：
Circulation. Cardiovascular quality and outcomes
影响因子：
--
作者：
Turan TN;Lynn MJ;Nizam A;Lane B;Egan BM;Le NA;Lopes-Virella MF;Hermayer KL;Benavente O;White CL;Brown WV;Caskey MF;Steiner MR;Vilardo N;Stufflebean A;Derdeyn CP;Fiorella D;Janis S;Chimowitz MI;SAMMPRIS Investigators
通讯作者：
SAMMPRIS Investigators
影响因子：
158.5
作者：
Wadden, TA;Berkowitz, RI;Stunkard, AJ
通讯作者：
Stunkard, AJ
DOI：
10.1016/j.jstrokecerebrovasdis.2011.05.001
发表时间：
2011-07
影响因子：
2.5
作者：
Chimowitz, Marc I.;Lynn, Michael J.;Turan, Tanya N.;Fiorella, David;Lane, Bethany F.;Janis, Scott;Derdeyn, Colin P.
通讯作者：
Derdeyn, Colin P.
神经科医生监督、护士病例管理的中风风险降低计划的需求和临床有效性
影响因子：
8.3
作者：
E. F. Lafranchise;Wallette G Widener;B. Franklin;R. Salmon;R. Leighton;C. D. English;N. Gordon
通讯作者：
N. Gordon